N
Nicolas Rouleau
Researcher at Tufts University
Publications - 48
Citations - 397
Nicolas Rouleau is an academic researcher from Tufts University. The author has contributed to research in topics: Medicine & Induced pluripotent stem cell. The author has an hindex of 8, co-authored 42 publications receiving 268 citations. Previous affiliations of Nicolas Rouleau include Laurentian University & Algoma University.
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A 3D human brain-like tissue model of herpes-induced Alzheimer's disease.
Dana M. Cairns,Nicolas Rouleau,Rachael N. Parker,Katherine G. Walsh,Lee Gehrke,David L. Kaplan +5 more
TL;DR: A herpes-induced tissue model of AD is reported that mimics human disease with multicellular amyloid plaque–like formations, gliosis, neuroinflammation, and decreased functionality, completely in the absence of any exogenous mediators of AD.
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A Long-Living Bioengineered Neural Tissue Platform to Study Neurodegeneration.
Nicolas Rouleau,William L. Cantley,Volha Liaudanskaya,Alexander N. Berk,Chuang Du,William Rusk,Emily Peirent,Cole Koester,Thomas J.F. Nieland,David L. Kaplan +9 more
TL;DR: It can be concluded that the long-term stability of the platform is suited to study chronic brain disease including neurodegeneration.
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Electromagnetic fields as structure-function zeitgebers in biological systems: environmental orchestrations of morphogenesis and consciousness
Nicolas Rouleau,Blake T. Dotta +1 more
TL;DR: Evidence of EM influence on cells and the integration of whole systems is described and it is suggested the growing literature of EM effects on biological systems has significant implications to the cell and its functional aggregates.
Journal Article
Article Experimental Demonstration of Potential Entanglement of Brain Activity over 300 Km for Pairs of Subjects Sharing the Same Circular Rotating, Angular Accelerating Magnetic Fields: Verification by s_LORETA, QEEG Measurements
TL;DR: In this article, the authors measured the potential energy from the applied magnetic field within a volume of about 0.13 cc (125 mm 3 ) and calculated that the induced energy is equivalent to about 10 -20 J per neuron.
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Modeling Controlled Cortical Impact Injury in 3D Brain-Like Tissue Cultures.
Volha Liaudanskaya,Joon Yong Chung,Craig Mizzoni,Nicolas Rouleau,Alexander N. Berk,Limin Wu,Julia A. Turner,Irene Georgakoudi,Michael J. Whalen,Thomas J.F. Nieland,David L. Kaplan +10 more
TL;DR: Evidence is provided that the 3D brain‐like culture system mimicked many aspects of in vivo responses to CCI, providing evidence that the model can be used to study the molecular, cellular, and functional sequelae of TBI, opening up new possibilities for discovery of therapeutics.