Nicole B. Kingsley

TL;DR: In this article , the authors examined the relationship between histone modifications and transcription using experimental perturbations combined with sensitive machine-learning tools and found that transcription is required for active histone modification.

TL;DR: The histone marks identified in this study represent some of the first resources for tissue-specific regulation within the equine genome and can be used to advance equine studies investigating health, performance, reproduction, and other traits of economic interest in the horse.

TL;DR: Age, coat pattern, and genetics are major risk factors for the diagnosis and classification of ERU in the Appaloosa.

TL;DR: Using imputation as an interpretative tool uncovered cell-type specific differences in how the PRC2-dependent repressive mark, H3K27me3, corresponds to transcription, and revealed that transcription initiation requires both chromatin accessibility and an active chromatin environment demonstrating that initiation is less promiscuous than previously thought.

TL;DR: In this paper, the authors used full thickness skin biopsies to isolate, culture and cryopreserve dermal fibroblasts from two adult Thoroughbred stallions.