Colin Kern

TL;DR: An exceptionally slow rate of genome evolution within crocodilians at all levels is observed, consistent with a single underlying cause of a reduced rate of evolutionary change rather than intrinsic differences in base repair machinery.

TL;DR: While lncRNAs are less conserved than protein-coding genes, a set of positionally conserved lnc RNAs were identified among chickens, cattle, and pigs with potential functions related to chromatin structure and gene regulation.

TL;DR: The Functional Annotation of Animal Genomes consortium was formed to collaboratively annotate the functional elements in animal genomes, starting with domesticated animals as mentioned in this paper, and a set of regulatory elements are functionally conserved independent of divergence between species, and tissue-specific transcription factor occupancy at regulatory elements and their predicted target genes are also conserved.

TL;DR: In this paper, the authors explore the sequence requirements of CCCTC-mediated transcriptional insulation using a sensitive insulator reporter in mouse embryonic stem cells and find that insulation potency depends on the number of CTCF-binding sites in tandem.

TL;DR: It is observed that the timing of the DNA transposon expansion and the resulting introduction of novel p/miRNAs coincide with the rapid diversification of the family Vespertilionidae, and a mechanism for introducing functional genomic variation rapidly through the expansion ofDNA transposons that fits within the TE-thrust hypothesis is suggested.