N
Nicole C. Roy
Researcher at Massey University
Publications - 231
Citations - 5949
Nicole C. Roy is an academic researcher from Massey University. The author has contributed to research in topics: Microbiome & Gene expression. The author has an hindex of 32, co-authored 212 publications receiving 4655 citations. Previous affiliations of Nicole C. Roy include University of Auckland & AgResearch.
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Journal ArticleDOI
Regulation of Tight Junction Permeability by Intestinal Bacteria and Dietary Components
Dulantha Ulluwishewa,Rachel C. Anderson,Warren C. McNabb,Warren C. McNabb,Paul J. Moughan,Jerry M. Wells,Nicole C. Roy +6 more
TL;DR: The human intestinal epithelium is formed by a single layer of epithelial cells that separates the intestinal lumen from the underlying lamina propria, which is sealed by tight junctions (TJ), which regulate the permeability of the intestinal barrier.
Journal ArticleDOI
Lactobacillus plantarum MB452 enhances the function of the intestinal barrier by increasing the expression levels of genes involved in tight junction formation
Rachel C. Anderson,Adrian L. Cookson,Warren C. McNabb,Warren C. McNabb,Zaneta Park,Mark McCann,William J. Kelly,Nicole C. Roy,Nicole C. Roy +8 more
TL;DR: This research indicates that enhancing the expression of genes involved in tight junction signalling is a possible mechanism by which L. plantarum MB452 improves intestinal barrier function.
Journal ArticleDOI
The role of cell surface architecture of lactobacilli in host-microbe interactions in the gastrointestinal tract.
Ranjita Sengupta,Eric Altermann,Eric Altermann,Rachel C. Anderson,Warren C. McNabb,Warren C. McNabb,Paul J. Moughan,Nicole C. Roy +7 more
TL;DR: Multiple cell surface-associated molecules have been implicated in the adherence of lactobacilli to the GIT lining, immunomodulation, and protective effects on intestinal epithelial barrier function.
Journal ArticleDOI
Lactobacillus plantarum DSM 2648 is a potential probiotic that enhances intestinal barrier function
Rachel C. Anderson,Adrian L. Cookson,Warren C. McNabb,Warren C. McNabb,William J. Kelly,Nicole C. Roy,Nicole C. Roy +6 more
TL;DR: The aim of this research was to identify bacterial isolates having the potential to improve intestinal barrier function and to identify bacteria strains and human oral isolates screened for their ability to enhance tight junction integrity as measured by the transepithelial electrical resistance (TEER) assay.
Journal ArticleDOI
Can Nutritional Modulation of Maternal Intestinal Microbiota Influence the Development of the Infant Gastrointestinal Tract
Caroline Thum,Adrian L. Cookson,Adrian L. Cookson,Don Otter,Warren C. McNabb,Warren C. McNabb,Alison J. Hodgkinson,Jolon M. Dyer,Jolon M. Dyer,Nicole C. Roy,Nicole C. Roy +10 more
TL;DR: In this paper, the influence of maternal GIT microbiota during the pre- and postpartum periods on the colonization of the infant GIT was examined and the manipulation of the maternal microbiota composition through the use of probiotics and/or prebiotics and subsequent consequences for the health of the offspring.