N
Nicole Thomasset
Researcher at French Institute of Health and Medical Research
Publications - 35
Citations - 2957
Nicole Thomasset is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: SEMA3A & Semaphorin. The author has an hindex of 21, co-authored 35 publications receiving 2791 citations. Previous affiliations of Nicole Thomasset include Claude Bernard University Lyon 1.
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Journal ArticleDOI
Use of MTT colorimetric assay to measure cell activation
Denis Gerlier,Nicole Thomasset +1 more
TL;DR: This analysis of MTT cleavage by viable cells suggests that the colorimetric MTT test can be useful to quantify the activation level of cells, independently of proliferation.
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Collapsin response mediator proteins (CRMPs): involvement in nervous system development and adult neurodegenerative disorders.
Emmanuelle Charrier,Sophie Reibel,Véronique Rogemond,M. Aguera,Nicole Thomasset,Jérôme Honnorat +5 more
TL;DR: The members of the collapsin response mediator protein (CRMP) family—five cytosolic phosphoproteins—are highly expressed throughout brain development and are altered in neurodegenerative diseases, and these proteins may be of key importance in the physiopathology of the adult nervous system.
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Semaphorin 3A-vascular endothelial growth factor-165 balance mediates migration and apoptosis of neural progenitor cells by the recruitment of shared receptor.
Dominique Bagnard,Catherine Vaillant,Seng-Thuon Khuth,Nathalie Dufay,Marion Lohrum,Andreas W. Püschel,Marie-Françoise Belin,Jürgen Bolz,Nicole Thomasset +8 more
TL;DR: The results indicate that the balance between guidance molecules and angiogenic factors can modulate the migration, apoptosis (or survival, and proliferation of neural progenitor cells through shared receptors.
Journal ArticleDOI
Spatiotemporal expression patterns of metalloproteinases and their inhibitors in the postnatal developing rat cerebellum.
TL;DR: Regional and cell-specific expression of MMPs and TIMPs closely reflects the successive stages of cerebellar development, thereby suggesting a pivotal role for ECM proteolysis in brain development and plasticity.
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MMP-9 deficiency affects axonal outgrowth, migration, and apoptosis in the developing cerebellum.
Catherine Vaillant,Claire Meissirel,Mireille Mutin,Marie-Françoise Belin,Leif R. Lund,Nicole Thomasset +5 more
TL;DR: It is shown that expression of MMP-9 is spatiotemporally related to cerebellar granule cell migration during postnatal development and direct evidence for a physiological role of M MP-9 in neuronal precursor migration and apoptosis in the developing cerebellum is provided.