N
Niek de Vries
Researcher at University of Amsterdam
Publications - 85
Citations - 8149
Niek de Vries is an academic researcher from University of Amsterdam. The author has contributed to research in topics: Medicine & Rheumatoid arthritis. The author has an hindex of 29, co-authored 66 publications receiving 7140 citations. Previous affiliations of Niek de Vries include Academic Medical Center & VU University Amsterdam.
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Journal ArticleDOI
Prevention of rheumatoid arthritis: A systematic literature review of preventive strategies in at-risk individuals.
TL;DR: In this article , a systematic literature review (SLR) was performed to understand the feasibility of preventive treatment in at-risk individuals, taking into account recently performed studies and ongoing clinical trials, as well as patient perspectives.
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Increased Frequency of CD4+ Follicular Helper T and CD8+ Follicular T Cells in Human Lymph Node Biopsies during the Earliest Stages of Rheumatoid Arthritis
Dornatien Chuo Anang,Tamara H. Ramwadhdoebe,J Hähnlein,Bo J van Kuijk,Noortje A. M. Smits,Krijn P. van Lienden,Mario Maas,Danielle M. Gerlag,Paul P. Tak,Niek de Vries,Lisa G. M. van Baarsen +10 more
TL;DR: It is suggested that Tfh cells may present a novel rationale for therapeutic targeting during the preclinical stage of RA to prevent further disease progression.
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RA-relevant T cell responses to type II collagen can be influenced by post-translational modifications.
Karine Chemin,Inka Albrecht,Sabrina Pollastro,Niek de Vries,Rikard Holmdahl,Vivianne Malmström +5 more
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The Germinal Center Milieu in Rheumatoid Arthritis: The Immunological Drummer or Dancer?
Dornatien C. Anang,Giulia Balzaretti,Antoine H C van Kampen,Niek de Vries,Paul L. Klarenbeek +4 more
TL;DR: In this paper, the role of Germinal Centers (GCs) in RA is discussed and various GC processes can result in aberrant production of B cells that possess autoreactive properties and might result in the production of RA related autoantibodies.
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Characterization and Monitoring of Antigen-Responsive T Cell Clones Using T Cell Receptor Gene Expression Analysis.
Sabrina Pollastro,Marie de Bourayne,Giulia Balzaretti,Aldo Jongejan,Barbera D. C. van Schaik,Ilse Therésia Gabriëla Niewold,Antoine H C van Kampen,Bernard Maillere,Niek de Vries +8 more
TL;DR: In this article, the authors used a UMI-based protocol to perform repertoire analysis on experimental replicates and demonstrated that the addition of IL-4 after antigen stimulation drives the expansion of T cell clones encoding unique receptor sequences.