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Nikolin Oberleitner
Researcher at Vienna University of Technology
Publications - 7
Citations - 574
Nikolin Oberleitner is an academic researcher from Vienna University of Technology. The author has contributed to research in topics: Limonene & Caenorhabditis elegans. The author has an hindex of 6, co-authored 7 publications receiving 510 citations. Previous affiliations of Nikolin Oberleitner include Durham University.
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Journal ArticleDOI
Cascade catalysis – strategies and challenges en route to preparative synthetic biology
Jan Muschiol,Christin Peters,Nikolin Oberleitner,Marko D. Mihovilovic,Uwe T. Bornscheuer,Florian Rudroff +5 more
TL;DR: This review will focus on major contributions in the field of cascade reactions over the last three years.
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Excessive folate synthesis limits lifespan in the C. elegans: E. coli aging model
Bhupinder Virk,Gonçalo D S Correia,Gonçalo D S Correia,David P. Dixon,Inna Feyst,Jie Jia,Nikolin Oberleitner,Zoe Briggs,Emily Hodge,Robert Edwards,John M. Ward,David Gems,David Weinkove,David Weinkove +13 more
TL;DR: It is suggested that microbial folate synthesis is a pharmacologically accessible target to slow animal aging without detrimental effects.
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An Enzymatic Toolbox for Cascade Reactions: A Showcase for an In Vivo Redox Sequence in Asymmetric Synthesis
Nikolin Oberleitner,Christin Peters,Jan Muschiol,Maria Kadow,Stefan Saß,Thomas Bayer,Patricia Schaaf,Naseem Iqbal,Florian Rudroff,Marko D. Mihovilovic,Uwe T. Bornscheuer +10 more
TL;DR: The prime novelty and major aim of the present study was to combine the efficiency of biosynthetic redox pathways, the modularity of synthesis by simple functional group transformations, and the substrate promiscuity of enzymes.
Journal ArticleDOI
From waste to value – direct utilization of limonene from orange peel in a biocatalytic cascade reaction towards chiral carvolactone
Nikolin Oberleitner,Anna K. Ressmann,Katharina Bica,Peter Gaertner,Marco W. Fraaije,Uwe T. Bornscheuer,Florian Rudroff,Marko D. Mihovilovic +7 more
TL;DR: This proof of concept study demonstrates direct utilization of limonene containing waste product orange peel as starting material for a biocatalytic cascade reaction that produces chiral carvolactone, a promising building block for thermoplastic polymers.
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In vitro characterization of an enzymatic redox cascade composed of an alcohol dehydrogenase, an enoate reductases and a Baeyer-Villiger monooxygenase
TL;DR: An enzyme cascade in vivo as well as in vitro for biorenewable polyesters production was compared and Mechanistic insights were gained for the presented cascade.