Journal ArticleDOI
Cascade catalysis – strategies and challenges en route to preparative synthetic biology
Jan Muschiol,Christin Peters,Nikolin Oberleitner,Marko D. Mihovilovic,Uwe T. Bornscheuer,Florian Rudroff +5 more
TLDR
This review will focus on major contributions in the field of cascade reactions over the last three years.About:
This article is published in Chemical Communications.The article was published on 2015-03-19. It has received 265 citations till now.read more
Citations
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I and i
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Journal ArticleDOI
Role of Biocatalysis in Sustainable Chemistry
Roger A. Sheldon,John M. Woodley +1 more
TL;DR: Based on the principles and metrics of green chemistry and sustainable development, biocatalysis is both a green and sustainable technology and its broader application will be further stimulated in the future by the emerging biobased economy.
Journal ArticleDOI
Substrate channelling as an approach to cascade reactions.
Ian Wheeldon,Shelley D. Minteer,Scott Banta,Scott Calabrese Barton,Plamen Atanassov,Matthew S. Sigman +5 more
TL;DR: The incorporation of substrate channelling into synthetic cascades is a rapidly developing concept, and recent examples of the fabrication of cascades with controlled diffusion and flux of intermediates are presented.
Journal ArticleDOI
Artificial Biocatalytic Linear Cascades for Preparation of Organic Molecules
TL;DR: The review introduces a systematic classification of the cascades according to the number of enzymes in the linear sequence and differentiates between cascades involving exclusively enzymes and combinations of enzymes with non-natural catalysts or chemical steps.
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Opportunities and challenges for combining chemo- and biocatalysis
Florian Rudroff,Marko D. Mihovilovic,Harald Gröger,Radka Snajdrova,Hans Iding,Uwe T. Bornscheuer +5 more
TL;DR: This Review focuses on efforts to combine chemo- and biocatalysts, outlining the opportunities achievable by this approach and also efforts to overcome any incompatibilities between these different systems.
References
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I and i
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Journal ArticleDOI
What is flux balance analysis
TL;DR: This primer covers the theoretical basis of the approach, several practical examples and a software toolbox for performing the calculations.
Journal ArticleDOI
Green Chemistry: Principles and Practice
Paul T. Anastas,Nicolas Eghbali +1 more
TL;DR: The concepts of design and the scientific philosophy of Green Chemistry are covered with a set of illustrative examples and the challenge of using the Principles as a cohesive design system is discussed.