Nils-Olof Bengtsson

TL;DR: Breast cancer radiotherapy has, at least until recently, increased the risk of developing ischaemic heart disease, pericarditis and valvular disease and women with ischaemia heart disease before breast cancer diagnosis may have incurred higher risks than others.

TL;DR: It is concluded that breast cancer lymph node metastases generally overexpress HER2 to the same extent as the corresponding primary tumours, and this also seems to be the case when distant metastases are considered.

TL;DR: It is suggested that cyclin D1 overexpression predicts for tamoxifen treatment resistance in breast cancer, which is in line with recent experimental data using breast cancer cell lines and overeexpression systems.

TL;DR: Among the 2046 patients randomly assigned to the 5-year group all-cause mortality, breast cancer-specific mortality, and the incidence of contralateral breast cancer were reduced, compared with those among 2129 patients randomized in the 2- year group, butthe incidence of endometrial cancer was increased.

TL;DR: The purpose of this study was to evaluate amplification of topoisomerase IIalpha (TOP2A) and HER2 genes as predictors of response to chemotherapy in advanced breast cancer.