Nina Lundbom

TL;DR: In this article, a method was developed to accurately predict non-alcoholic fatty liver disease (NAFLD) and liver fat content based on routinely available clinical and laboratory data and to test whether knowledge of the recently discovered genetic variant in the PNPLA3 gene (rs738409) increases accuracy of the prediction.

TL;DR: A short-term intervention with an isocaloric low-carbohydrate diet with increased protein content in obese subjects with NAFLD and the resulting alterations in metabolism and the gut microbiota are characterized using a multi-omics approach to highlight the potential of exploring diet-microbiota interactions for treatingNAFLD.

TL;DR: It is hypothesized that dietary macronutrient composition influences the pathways, mediators, and magnitude of weight gain-induced changes in IHTG, and decreased intakes of SAT could be beneficial in reducing I HTG and the associated risk of diabetes.

TL;DR: In this paper, the authors examined whether overfeeding overweight subjects with simple sugars increases liver fat and de novo lipogenesis (DNL) and whether this is reversible by weight loss and found that the increase in liver fat was proportional to that in DNL.

TL;DR: In this paper, the authors examined subcutaneous adipose tissue (SAT) samples from healthy monozygotic twin pairs, 22.8-36.2 years of age, who were discordant (ΔBMI >3 kg/m2, mean length of discordance 6.3 ± 0.3 years, n = 26) and concordant for body weight, and assessed their detailed mitochondrial metabolic characteristics: mitochondrial-related transcriptomes with dysregulated pathways, mitochondrial DNA (mtDNA) amount, mtDNA-encoded transcripts, and mitochondrial oxidative phosph