G
Göran Bergström
Researcher at University of Gothenburg
Publications - 249
Citations - 10085
Göran Bergström is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Population & Kidney. The author has an hindex of 39, co-authored 224 publications receiving 7763 citations. Previous affiliations of Göran Bergström include Cardiovascular Institute of the South & Monash University, Clayton campus.
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Journal ArticleDOI
Gut metagenome in European women with normal, impaired and diabetic glucose control
Fredrik Karlsson,Valentina Tremaroli,Intawat Nookaew,Göran Bergström,Carl Johan Behre,Björn Fagerberg,Jens Nielsen,Fredrik Bäckhed,Fredrik Bäckhed +8 more
TL;DR: This work uses shotgun sequencing to characterize the faecal metagenome of 145 European women with normal, impaired or diabetic glucose control, and develops a mathematical model based on metagenomic profiles that identified T2D with high accuracy.
Journal ArticleDOI
Endothelial PDGF-B retention is required for proper investment of pericytes in the microvessel wall.
Per Lindblom,Holger Gerhardt,Stefan Liebner,Alexandra Abramsson,Maria Enge,Mats Hellström,Gudrun Bäckström,Simon Fredriksson,Ulf Landegren,Henrik C. Nyström,Göran Bergström,Elisabetta Dejana,Arne Östman,Per Lindahl,Christer Betsholtz +14 more
TL;DR: It is concluded that retention of PDGF-B in microvessels is essential for proper recruitment and organization of pericytes and for renal and retinal function in adult mice.
Journal ArticleDOI
Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1.
Ara Koh,Antonio Molinaro,Marcus Ståhlman,Muhammad Tanweer Khan,Caroline Schmidt,Louise Mannerås-Holm,Hao Wu,Alba Carreras,Heeyoon Jeong,Louise E. Olofsson,Per-Olof Bergh,Victor E. A. Gerdes,Annick V. Hartstra,Maurits de Brauw,Rosie Perkins,Max Nieuwdorp,Max Nieuwdorp,Max Nieuwdorp,Göran Bergström,Fredrik Bäckhed,Fredrik Bäckhed +20 more
TL;DR: It is shown that imidazole propionate is produced from histidine in a gut simulator at higher concentrations when using fecal microbiota from subjects with versus without type 2 diabetes and that it impairs glucose tolerance when administered to mice.
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An Integrated Understanding of the Rapid Metabolic Benefits of a Carbohydrate-Restricted Diet on Hepatic Steatosis in Humans
Adil Mardinoglu,Hao Wu,Elias Björnson,Cheng Zhang,Antti Hakkarainen,Sari M. Räsänen,Sunjae Lee,Rosellina Margherita Mancina,Mattias Bergentall,Kirsi H. Pietiläinen,Sanni Söderlund,Niina Matikainen,Marcus Ståhlman,Per Olof Bergh,Martin Adiels,Brian D. Piening,Marit Granér,Nina Lundbom,Kevin Jon Williams,Stefano Romeo,Jens Nielsen,Michael Snyder,Mathias Uhlén,Göran Bergström,Rosie Perkins,Hanns-Ulrich Marschall,Fredrik Bäckhed,Marja-Riitta Taskinen,Jan Borén +28 more
TL;DR: A short-term intervention with an isocaloric low-carbohydrate diet with increased protein content in obese subjects with NAFLD and the resulting alterations in metabolism and the gut microbiota are characterized using a multi-omics approach to highlight the potential of exploring diet-microbiota interactions for treatingNAFLD.
Journal ArticleDOI
The human secretome
Mathias Uhlén,Mathias Uhlén,Mathias Uhlén,Max J. Karlsson,Andreas Hober,Anne-Sophie Svensson,Julia Scheffel,David Kotol,Wen Zhong,Abdellah Tebani,Linnéa Strandberg,Fredrik Edfors,Fredrik Edfors,Evelina Sjöstedt,Jan Mulder,Adil Mardinoglu,Anna Berling,Siri Ekblad,Melanie Dannemeyer,Sara Kanje,Johan Rockberg,Magnus Lundqvist,Magdalena Malm,Anna-Luisa Volk,Peter Nilsson,Anna Månberg,Tea Dodig-Crnković,Elisa Pin,Martin Zwahlen,Per Oksvold,Kalle von Feilitzen,Ragna S. Häussler,Mun-Gwan Hong,Cecilia Lindskog,Fredrik Pontén,Borbala Katona,Jimmy Vuu,Emil Lindström,Jens Nielsen,Jonathan L. Robinson,Burcu Ayoglu,Diana Mahdessian,Devin P. Sullivan,Peter Thul,Frida Danielsson,Charlotte Stadler,Emma Lundberg,Göran Bergström,Göran Bergström,Anders Gummesson,Bjørn G. Voldborg,Hanna Tegel,Sophia Hober,Björn Forsström,Jochen M. Schwenk,Linn Fagerberg,Åsa Sivertsson +56 more
TL;DR: A comprehensive analysis of proteins predicted to be secreted in human cells, which provides information about their final localization in the human body, including the proteins actively secreted to peripheral blood.