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Ninel Z. Gregori
Researcher at Bascom Palmer Eye Institute
Publications - 12
Citations - 1319
Ninel Z. Gregori is an academic researcher from Bascom Palmer Eye Institute. The author has contributed to research in topics: Visual acuity & Cataract surgery. The author has an hindex of 7, co-authored 12 publications receiving 1132 citations.
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Journal ArticleDOI
Human embryonic stem cell-derived retinal pigment epithelium in patients with age-related macular degeneration and Stargardt's macular dystrophy: follow-up of two open-label phase 1/2 studies
Steven D. Schwartz,Carl D. Regillo,Byron L. Lam,Dean Eliott,Philip J. Rosenfeld,Ninel Z. Gregori,Jean-Pierre Hubschman,Janet L. Davis,Gad Heilwell,Marc J. Spirn,Joseph I. Maguire,Jane Bateman,Rosaleen Ostrick,Debra Morris,Matthew Vincent,Eddy Anglade,Lucian V. Del Priore,Robert Lanza +17 more
TL;DR: The results suggest that hESC-derived cells could provide a potentially safe new source of cells for the treatment of various unmet medical disorders requiring tissue repair or replacement.
Journal ArticleDOI
Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR
Jasmina Cehajic-Kapetanovic,Kanmin Xue,Cristina Martinez-Fernandez de la Camara,Anika Nanda,Alexandra Davies,Laura J Wood,Anna Paola Salvetti,M. Dominik Fischer,James Aylward,Alun R. Barnard,Jasleen K Jolly,Edmond Luo,Brandon J. Lujan,Tuyen Ong,Aniz Girach,Graeme C.M. Black,Graeme C.M. Black,Ninel Z. Gregori,Janet L. Davis,Potyra R. Rosa,Andrew J. Lotery,Andrew J. Lotery,Byron L. Lam,Paulo E. Stanga,Paulo E. Stanga,Robert E MacLaren +25 more
TL;DR: Early results from a first-in-human retinal gene therapy trial for X-linked retinitis pigmentosa indicate that, at an intermediate dose, AAV8-RPGR is safe and in a subset of patients can lead to gains in visual function.
Journal ArticleDOI
Macular Spectral-domain Optical Coherence Tomography in Patients with X-linked Retinoschisis.
Ninel Z. Gregori,Audina M. Berrocal,Giovanni Gregori,Timothy G. Murray,Robert W. Knighton,Harry W. Flynn,Sander R. Dubovy,Carmen A. Puliafito,Philip J. Rosenfeld +8 more
TL;DR: SD-OCT localised the foveomacular retinoschisis in XLRS to the retinal layers deeper than the nerve fibre layer, which was seen most frequently in the inner nuclear layer in the present study.
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Relationship between the morphology of the foveal avascular zone, retinal structure, and macular circulation in patients with diabetes mellitus.
Nathan M. Bates,Jing Tian,William E. Smiddy,Wen Hsiang Lee,Gabor Mark Somfai,William J. Feuer,Joyce C. Shiffman,Ajay E. Kuriyan,Ninel Z. Gregori,Maja Kostic,Sandra Pineda,Delia Cabrera DeBuc +11 more
TL;DR: The results suggest a potential anisotropy in the mechanical properties of the diabetic retina with no retinopathy that may trigger the FAZ elongation in a preferred direction resulting in either thinning or thickening of intraretinal layers in the inner and outer segments of the retina as a result of autoregulation.
Journal ArticleDOI
Reproducibility and comparison of visual acuity obtained with sightbook mobile application to near card and snellen chart.
TL;DR: The discrepancy between SightBook mobile app and the clinic charts acuities may be large; however, the results are highly reproducible.