Noah R. Leigh

TL;DR: The results directly implicate noncoding RNA-mediated transcriptional regulation of gene expression as a fundamental control mechanism for physiologic processes, such as vascular development.

TL;DR: It is shown that the loss of CBS function in endothelial cells (ECs) leads to a significant down‐regulation of cellular hydrogen sulfide (H2S) by 50% and of glutathione (GSH) by 40%, highlighting the importance of CBS‐mediated protein S‐sulfhydration in maintaining vascular health and function.

TL;DR: This study has identified the first pair of MMP, and their putative MMP inhibitor RECK that functions together in NC cell migration.

TL;DR: Members of the Sry-related high mobility box (Sox) transcription factor family are shown as being transcriptional regulators of roundabout4 (robo4), a Robo gene family member that participates in sprouting angiogenesis in vivo, in zebrafish.

TL;DR: In this paper, the authors performed RNA analysis in whole zebrafish embryos that showed a wide expression pattern for cbsa and cbsb primarily along the embryonic axis of the developing embryo.