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Norihide Asano

Researcher at Nitto Denko

Publications -  13
Citations -  1058

Norihide Asano is an academic researcher from Nitto Denko. The author has contributed to research in topics: Micronucleus test & Micronucleus. The author has an hindex of 12, co-authored 13 publications receiving 1024 citations.

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Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (groups 1, 2A and 2B) the summary report of the 6th collaborative study by CSGMT/JEMS MMS. Collaborative Study of the Micronucleus Group Test. Mammalian Mutagenicity Study Group.

TL;DR: In the 6th MMS/CSGMT collaborative study as mentioned in this paper, IARC groups 1 (human carcinogen), 2A (probable human carcinogen) and 2B (possible human carcinogens) were selected from 100 commercially available chemicals and chemical groups on which there was little or no micronucleus assay data.
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Development of genotoxicity assay systems that use aquatic organisms

TL;DR: In a field study, it is shown that the micronucleus assay is applicable to freshwater and marine fishes and that gill cells are more sensitive than hematopoietic cells to micron nuclei-inducing agents.
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Evaluation of the rat micronucleus test with bone marrow and peripheral blood: Summary of the 9th collaborative study by CSGMT/JEMS. MMS

TL;DR: The aim of the 9th collaborative study by CSGMT was to evaluate the suitability of the rat for the micronucleus test, with bone marrow and peripheral blood as the target organ.
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In vivo erythrocyte micronucleus assay III. Validation and regulatory acceptance of automated scoring and the use of rat peripheral blood reticulocytes, with discussion of non-hematopoietic target cells and a single dose-level limit test.

TL;DR: The working group discussed new aspects in the in vivo micronucleus test, including the regulatory acceptance of data derived from automated scoring, the use of flow cytometry, the suitability of rat peripheral blood reticulocytes to serve as the principal cell population for analysis, the establishment of in vivo MN assays in tissues other than bone marrow and blood, and the biological relevance of the single-dose-level test.