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Noriko Hidaka
Researcher at University of Michigan
Publications - 6
Citations - 3997
Noriko Hidaka is an academic researcher from University of Michigan. The author has contributed to research in topics: Gene mapping & Genetic linkage. The author has an hindex of 6, co-authored 6 publications receiving 3880 citations. Previous affiliations of Noriko Hidaka include Howard Hughes Medical Institute.
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Journal ArticleDOI
Identification of the cystic fibrosis gene: Chromosome walking and jumping
Johanna M. Rommens,Michael C. Iannuzzi,Batsheva Kerem,Mitchell L. Drumm,Georg Melmer,Michael Dean,Richard Rozmahel,Jeffery L. Cole,Dara Kennedy,Noriko Hidaka,Martha Zsiga,Manuel Buchwald,John R. Riordan,Lap-Chee Tsui,Francis S. Collins +14 more
TL;DR: Several transcribed sequences and conserved segments were identified in this cloned region and one corresponds to the cystic fibrosis gene and spans approximately 250,000 base pairs of genomic DNA.
Journal ArticleDOI
Identification of the cystic fibrosis gene: Chromosome walking and jumping
Johanna M. Rommens,Michael C. Iannuzzi,Batsheva Kerem,Mitchell L. Drumm,Georg Melmer,Michael Dean,Richard Roxmahel,Jeffery L. Cole,Dara Kennedy,Noriko Hidaka,Martha Zsiga,Manuel Buchwald,John R. Riordan,Lap-Chee Tsui,Francis S. Collins +14 more
TL;DR: Several transcribed sequences and conserved segments were identified in this cloned region and one corresponds to the cystic fibrosis gene and spans approximately 250,000 base pairs of genomic DNA.
Journal Article
Two frameshift mutations in the cystic fibrosis gene.
Michael C. Iannuzzi,Robert C. Stern,Francis S. Collins,Catherine Tom Hon,Noriko Hidaka,Theresa V. Strong,Lisa Becker,Mitchell L. Drumm,Marga Belle White,Bernard Gerrard,Michael Dean +10 more
TL;DR: Two frameshift mutations are identified in exon 7 of CFTR that are predicted to shift the reading frame of the protein and to introduce UAA(ochre) termination codons at residues 369 and 368.
Journal Article
Analysis of the relationship of von Willebrand disease (vWD) and hereditary hemorrhagic telangiectasia and identification of a potential type IIA vWD mutation (IIe865 to Thr).
Michael C. Iannuzzi,Noriko Hidaka,Michael Boehnke,Mary E. Bruck,Wahid Hanna,Francis S. Collins,David Ginsburg +6 more
TL;DR: Two families with members affected with both von Willebrand disease and hereditary hemorrhagic telangiectasia are studied by RFLP analysis to determine whether there is a molecular basis for the association of vWD and HHT.
Journal Article
Isolation of additional polymorphic clones from the cystic fibrosis region, using chromosome jumping from D7S8.
Michael C. Iannuzzi,Michael Dean,Mitchell L. Drumm,Noriko Hidaka,Jeffery L. Cole,A. Perry,C. Stewart,B. Gerrard,Frank H. Collins +8 more
TL;DR: Though the newly described RFLPs are in considerable linkage disequilibrium with D 7S8 polymorphisms, they increase the informativeness of genetic markers in the D7S8 region and should be useful in prenatal diagnosis.