O
O. N. Khokhlova
Researcher at Russian Academy of Sciences
Publications - 22
Citations - 108
O. N. Khokhlova is an academic researcher from Russian Academy of Sciences. The author has contributed to research in topics: Bone marrow & Medicine. The author has an hindex of 3, co-authored 18 publications receiving 69 citations.
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Journal ArticleDOI
COG1410, a novel apolipoprotein-E mimetic, improves functional and morphological recovery in a rat model of focal brain ischemia.
Elena A Tukhovskaya,Alexey Y. Yukin,O. N. Khokhlova,Arkady N. Murashev,Michael P. Vitek,Michael P. Vitek +5 more
TL;DR: Using an intraluminal middle cerebral occlusion model in rats, it is found that a single intravenous injection of COG1410 at 120 min post‐MCAO significantly improved vestibulomotor function, decreased poststroke locomotor asymmetry, and decreased infarct volume of the ipsilateral hemisphere.
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Using Tiletamine-Zolazepam-Xylazine Anesthesia Compared to CO 2 -inhalation for Terminal Clinical Chemistry, Hematology, and Coagulation Analysis in Mice.
O. N. Khokhlova,Elena A Tukhovskaya,I. N. Kravchenko,E. S. Sadovnikova,Irina A. Pakhomova,E. A. Kalabina,A. V. Lobanov,Elvira R. Shaykhutdinova,Alina M Ismailova,Arkady N. Murashev +9 more
TL;DR: The studied method of mouse anesthesia, followed by terminal blood sampling and analysis of clinical pathology parameters, suggests that TZX is a good alternative to CO2 inhalation in toxicological and other nonclinical studies.
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A novel view of the problem of osteoarthritis in experimental rat model
V. A. Palikov,Y. A. Palikova,Natalya A. Borozdina,Elena N. Nesmeyanova,Pavel A. Rudenko,Vitalij A. Kazakov,E. A. Kalabina,Mikhail V. Bukatin,Tatyana Yu. Zharmukhamedova,O. N. Khokhlova,Igor A. Dyachenko +10 more
TL;DR: The following functional tests were identified as the most significant and sufficient to assess the development of MIA-induced osteoarthritis and analgesic efficacy of NSAIDs: incapacitance test, allodynia test (von Frey filaments), measurement of hind limb grip strength and measurement of the diameter of the inflamed knee joint.
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Bone marrow-derived multipotent stromal cells promote myocardial fibrosis and reverse remodeling of the left ventricle.
Timur Fatkhudinov,G. B. Bol’shakova,I. V. Arutyunyan,Andrey Elchaninov,A. V. Makarov,Evgeniya Kananykhina,O. N. Khokhlova,Arkady N. Murashev,V. V. Glinkina,D. V. Gol’dshtein,Gennady T. Sukhikh +10 more
TL;DR: Left ventricular wall thickening associated with reduced dilatation index was promoted by transplantation of the autologous cells and stimulates left ventricular reverse remodeling.
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Effect of Standard and High-Fat Diets during Modeling of Streptozotocin-Induced Diabetes in Rats on the Development of Complications.
Elvira R. Shaykhutdinova,V. A. Palikov,Y. A. Palikova,N. A. Borozdina,I. N. Kravchenko,E. S. Sadovnikova,I. A. Pakhomova,P. A. Rudenko,V. A. Kazakov,T. Y. Zharmukhamedova,O. N. Khokhlova,Igor A. Dyachenko +11 more
TL;DR: For evaluation of the effect of high-fat diet on the development of diabetic complications, the rats were maintained on standard or highfat diet for 3 weeks and the results showed significant changes in hematological parameters, physical and biochemical parameters of the urine, and in development of thermal allodynia were different after 15-week standard and high fat diets as mentioned in this paper.