O
Ofir Harari
Researcher at Cytel
Publications - 40
Citations - 960
Ofir Harari is an academic researcher from Cytel. The author has contributed to research in topics: Randomized controlled trial & Medicine. The author has an hindex of 10, co-authored 29 publications receiving 296 citations. Previous affiliations of Ofir Harari include Simon Fraser University & Tel Aviv University.
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Journal ArticleDOI
Effect of early treatment with fluvoxamine on risk of emergency care and hospitalisation among patients with COVID-19: the TOGETHER randomised, platform clinical trial.
M Helena Vasconcelos,Gilmar Reis,Eduardo Augusto dos Santos Moreira-Silva,Daniela Carla Medeiros Silva,Lehana Thabane,Aline Cruz Milagres,Thiago Santiago Ferreira,Castilho Vitor Quirino dos Santos,Vitoria Helena de Souza Campos,Ana Maria Ribeiro Nogueira,Ana Paula Figueiredo Guimaraes de Almeida,Eduardo Diniz Callegari,Adhemar Dias de Figueiredo Neto,Leonardo Cançado Monteiro Savassi,Maria Izabel Campos Simplicio,Luciene Barra Ribeiro,Rosemary Oliveira,Ofir Harari,Jamie I Forrest,Hinda Ruton,Sheila Sprague,Paula McKay,Alla V. Glushchenko,Craig R. Rayner,Craig R. Rayner,Eric J. Lenze,Angela M. Reiersen,Gordon H. Guyatt,Edward J Mills +28 more
TL;DR: The TOGETHER trial as discussed by the authors evaluated the efficacy of fluvoxamine versus placebo in preventing hospitalisation defined as either retention in a COVID-19 emergency setting or transfer to a tertiary hospital due to CoV-19.
Journal ArticleDOI
Systematic review of basket trials, umbrella trials, and platform trials: a landscape analysis of master protocols
Jay J H Park,Ellie Siden,Michael J. Zoratti,Louis Dron,Ofir Harari,Joel Singer,Richard T. Lester,Kristian Thorlund,Kristian Thorlund,Edward J Mills,Edward J Mills +10 more
TL;DR: The number of master protocols will continue to increase at a rapid pace over the upcoming decades and more efforts to improve awareness and training are needed to apply these innovative trial design methods to fields outside of oncology.
Journal ArticleDOI
Effect of Early Treatment With Hydroxychloroquine or Lopinavir and Ritonavir on Risk of Hospitalization Among Patients With COVID-19: The TOGETHER Randomized Clinical Trial.
Gilmar Reis,Eduardo Augusto dos Santos Moreira Silva,Daniela Carla Medeiros Silva,Lehana Thabane,Gurmit Singh,Jay J H Park,Jay J H Park,Jamie I Forrest,Jamie I Forrest,Ofir Harari,Castilho Vitor Quirino dos Santos,Ana Paula Figueiredo Guimaraes de Almeida,Adhemar Dias de Figueiredo Neto,Leonardo Cançado Monteiro Savassi,Aline Cruz Milagres,Mauro M. Teixeira,Maria Izabel Campos Simplicio,Luciene Barra Ribeiro,Rosemary Oliveira,Edward J Mills,Together Investigators +20 more
TL;DR: In this paper, a randomized clinical trial was conducted in Brazil to determine whether hydroxychloroquine or lopinavir-ritonavir reduces hospitalization among high-risk patients with early symptomatic COVID-19 in an outpatient setting.
Journal ArticleDOI
An overview of platform trials with a checklist for clinical readers
Jay J H Park,Ofir Harari,Louis Dron,Richard T. Lester,Kristian Thorlund,Edward J Mills,Edward J Mills +6 more
TL;DR: Key concepts of platform trials are described with case study discussion of two hallmark platform trials in STAMPEDE and I-SPY2 and a reader's guide to platform trials with a critical appraisal checklist is provided.
Journal ArticleDOI
Effectiveness and cost-effectiveness of group support psychotherapy delivered by trained lay health workers for depression treatment among people with HIV in Uganda: a cluster-randomised trial.
Etheldreda Nakimuli-Mpungu,Seggane Musisi,Kizito Wamala,James Okello,Sheila Ndyanabangi,Josephine Birungi,Mastula Nanfuka,Micheal Etukoit,Chrispus Mayora,Freddie Ssengooba,Ramin Mojtabai,Jean B. Nachega,Ofir Harari,Edward J Mills +13 more
TL;DR: Integration of cost-effective psychological treatments such as group support psychotherapy into existing HIV interventions might improve the mental health of people living with HIV in Uganda.