O
Olavi Ukkola
Researcher at Oulu University Hospital
Publications - 203
Citations - 7219
Olavi Ukkola is an academic researcher from Oulu University Hospital. The author has contributed to research in topics: Population & Ghrelin. The author has an hindex of 46, co-authored 184 publications receiving 6555 citations. Previous affiliations of Olavi Ukkola include University of Oulu & Pennington Biomedical Research Center.
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Journal ArticleDOI
Low Plasma Ghrelin Is Associated With Insulin Resistance, Hypertension, and the Prevalence of Type 2 Diabetes
TL;DR: It is concluded that low ghrelin is independently associated with type 2 diabetes, insulin concentration, insulin resistance, and elevated BP, and might have some role in the etiology of type 1 diabetes and the regulation of BP.
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Adiponectin: a link between excess adiposity and associated comorbidities?
Olavi Ukkola,Merja Santaniemi +1 more
TL;DR: It is shown that adiponectin has anti-inflammatory and antiatherogeneic effects as well as multiple beneficial effects on metabolism, and is shown to suppress macrophage-to-foam cell transformation and has an inhibitory effect on vascular smooth muscle cell proliferation.
Journal ArticleDOI
RAPID COMMUNICATIONS: Mutations in the Preproghrelin/Ghrelin Gene Associated with Obesity in Humans
Olavi Ukkola,Eric Ravussin,Peter Jacobson,Eric E. Snyder,Monique Chagnon,Lars Sjöström,Claude Bouchard +6 more
TL;DR: Evidence is provided that a low frequency sequence variation in the ghrelin gene could play a role in the etiology of obesity.
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Role of ghrelin polymorphisms in obesity based on three different studies.
Olavi Ukkola,Eric Ravussin,Peter Jacobson,Louis Pérusse,Tuomo Rankinen,Matthias H. Tschöp,Mark L. Heiman,Arthur S. Leon,Dabeeru C. Rao,James S. Skinner,Jack H. Wilmore,Lars Sjöström,Claude Bouchard +12 more
TL;DR: The preproghrelin Met72 carrier status seems to be protective against fat accumulation and associated metabolic comorbidities.
Journal ArticleDOI
Age, body mass index, race and other determinants of steroid hormone variability: the HERITAGE Family Study
Olavi Ukkola,Jacques Gagnon,Tuomo Rankinen,PA Thompson,Y Hong,Arthur S. Leon,D. C Rao,James S. Skinner,J. H. Wilmore,Claude Bouchard +9 more
TL;DR: It is concluded that age was the most important factor, followed by BMI, race and lifestyle factors in explaining steroid hormone variability.