O
Ole Paulsen
Researcher at University of Cambridge
Publications - 147
Citations - 14496
Ole Paulsen is an academic researcher from University of Cambridge. The author has contributed to research in topics: Long-term potentiation & Synaptic plasticity. The author has an hindex of 60, co-authored 142 publications receiving 12881 citations. Previous affiliations of Ole Paulsen include University of Oslo & Norwegian University of Science and Technology.
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Journal ArticleDOI
Expression and distribution of metabotropic GABA receptor subtypes GABABR1 and GABABR2 during rat neocortical development.
Guillermina López-Bendito,Ryuichi Shigemoto,A. Kulik,Ole Paulsen,Alfonso Fairén,Rafael Luján +5 more
TL;DR: The results indicate potentially important roles for the GABABRs in the regulation of migratory processes during corticogenesis and in the modulation of synaptic transmission during early development of cortical circuitry.
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Synaptic Currents in Anatomically Identified CA3 Neurons during Hippocampal Gamma Oscillations In Vitro
TL;DR: A recurrent mechanism of gamma oscillations, whereby spike timing is controlled primarily by inhibition in pyramidal cells and by excitation in interneurons is supported.
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Emergence of rich-club topology and coordinated dynamics in development of hippocampal functional networks in vitro.
TL;DR: The role of hubs during network development is investigated using multi-electrode arrays and functional connectivity analysis during spontaneous multi-unit activity (MUA) of dissociated primary mouse hippocampal neurons, confirming that hub nodes and rich-clubs may play an important role in coordinating functional dynamics at the microcircuit level.
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Hemisphere-specific optogenetic stimulation reveals left-right asymmetry of hippocampal plasticity.
Michael M. Kohl,Olivia A. Shipton,Olivia A. Shipton,Robert M. J. Deacon,J. Nicholas P. Rawlins,Karl Deisseroth,Ole Paulsen,Ole Paulsen +7 more
TL;DR: In this article, the authors used optogenetic tools to selectively stimulate axons of CA3 pyramidal cells originating in either left or right mouse hippocampus and found that left CA3 input produced more long-term potentiation at CA1 synapses than right CA3 inputs as a result of differential expression of GluN2B subunit-containing NMDA receptors.
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Double Dissociation of Spike Timing–Dependent Potentiation and Depression by Subunit-Preferring NMDA Receptor Antagonists in Mouse Barrel Cortex
Abhishek Banerjee,Rhiannon M. Meredith,Antonio Rodríguez-Moreno,Susanna B. Mierau,Yves Auberson,Ole Paulsen +5 more
TL;DR: An NMDA receptor subunit-dependent double dissociation of t-LTD and t- LTP mechanisms at layer 4-to-layer 2/3 synapses is demonstrated, and it is suggested that t- lTD is mediated by distinct molecular mechanisms at different synapses on the same postsynaptic neuron.