O
Ole Paulsen
Researcher at University of Cambridge
Publications - 147
Citations - 14496
Ole Paulsen is an academic researcher from University of Cambridge. The author has contributed to research in topics: Long-term potentiation & Synaptic plasticity. The author has an hindex of 60, co-authored 142 publications receiving 12881 citations. Previous affiliations of Ole Paulsen include University of Oslo & Norwegian University of Science and Technology.
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Journal ArticleDOI
The timing of external input controls the sign of plasticity at local synapses.
Jeehyun Kwag,Ole Paulsen +1 more
TL;DR: It is found that the timing of afferent input can bidirectionally control the sign of spike timing–dependent plasticity at local synapses in rat hippocampus, providing a means by which temporal information in external input can be encoded in the local matrix of synaptic weights.
Journal ArticleDOI
Presynaptic Self-Depression at Developing Neocortical Synapses
Antonio Rodríguez-Moreno,Antonio Rodríguez-Moreno,Antonio Rodríguez-Moreno,Ana González-Rueda,Abhishek Banerjee,A. Louise Upton,Michael T. Craig,Ole Paulsen,Ole Paulsen +8 more
TL;DR: Using sensory-evoked activity patterns recorded from the developing mouse cortex in vivo, the synaptic learning rule that is uncovered here relies solely on the presynaptic neuron and complements timing-based rules and is likely to play a role in the pruning of synaptic input during cortical development.
Journal ArticleDOI
Distinct roles of GABAB1a- and GABAB1b-containing GABAB receptors in spontaneous and evoked termination of persistent cortical activity.
Michael T. Craig,Michael T. Craig,Elizabeth W. Mayne,Elizabeth W. Mayne,Bernhard Bettler,Ole Paulsen,Ole Paulsen,Chris J. McBain +7 more
TL;DR: GABAB receptors containing the GABAB1a subunit contribute to spontaneous termination ofUP states and are essential for afferent‐evoked termination of UP states.
Journal ArticleDOI
Distinct mechanisms of spike timing-dependent LTD at vertical and horizontal inputs onto L2/3 pyramidal neurons in mouse barrel cortex
Abhishek Banerjee,Ana González-Rueda,Cassandra Sampaio-Baptista,Ole Paulsen,Antonio Rodríguez-Moreno,Antonio Rodríguez-Moreno +5 more
TL;DR: It is found that both vertical and horizontal inputs show STDP, but that they display different time windows for induction of timing‐dependent long‐term depression (t‐LTD), and it is suggested that these forms of plasticity may enable these two types of cortical synapses to support different functions.