O
Oliver Weingärtner
Researcher at University of Jena
Publications - 70
Citations - 1464
Oliver Weingärtner is an academic researcher from University of Jena. The author has contributed to research in topics: Cholesterol & Ezetimibe. The author has an hindex of 19, co-authored 63 publications receiving 1235 citations. Previous affiliations of Oliver Weingärtner include Saarland University & University of Oldenburg.
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Journal ArticleDOI
Vascular Effects of Diet Supplementation With Plant Sterols
Oliver Weingärtner,Dieter Lütjohann,Shengbo Ji,Nicole Weisshoff,Franka List,Thomas Sudhop,Klaus von Bergmann,Karen Gertz,Jochem König,Hans-Joachim Schäfers,Matthias Endres,Michael Böhm,Ulrich Laufs +12 more
TL;DR: Food supplementation with PSE impairs endothelial function, aggravates ischemic brain injury, effects atherogenesis in mice, and leads to increased tissue sterol concentrations in humans, so prospective studies are warranted that evaluate not only effects on cholesterol reduction, but also on clinical endpoints.
Journal ArticleDOI
Controversial role of plant sterol esters in the management of hypercholesterolaemia
TL;DR: Recently released guidelines are more critical of food supplementation with phytosterols and draw attention to significant safety issues, which have implications for the management of hypercholesterolaemia.
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Plant Sterols the Better Cholesterol in Alzheimer's Disease? A Mechanistical Study
Verena K. Burg,Heike S. Grimm,Tatjana L. Rothhaar,Sven Grösgen,Benjamin Hundsdörfer,Viola J. Haupenthal,Valerie C. Zimmer,Janine Mett,Oliver Weingärtner,Ulrich Laufs,Laus M. Broersen,Heikki Tanila,Tim Vanmierlo,Dieter Lütjohann,Tobias Hartmann,Marcus O. W. Grimm +15 more
TL;DR: Mice fed with stig masterol-enriched diets confirmed protective effects in vivo, suggesting that dietary intake of phytosterol blends mainly containing stigmasterol might be beneficial in preventing AD.
Journal ArticleDOI
Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.
Tim Vanmierlo,Tim Vanmierlo,Tim Vanmierlo,Oliver Weingärtner,Susanne M. A. van der Pol,Constanze Husche,Anja Kerksiek,Silvia Friedrichs,Eric J.G. Sijbrands,Harry Steinbusch,Harry Steinbusch,Marcus O. W. Grimm,Tobias Hartmann,Ulrich Laufs,Michael Böhm,Helga E. de Vries,Monique T. Mulder,Dieter Lütjohann,Dieter Lütjohann +18 more
TL;DR: Over a 6-month period, plant sterol accumulation in murine brain is virtually irreversible, and in vitro experiments with brain endothelial cell cultures showed that campesterol crossed the blood-brain barrier more efficiently than sitosterol.
Journal ArticleDOI
Cardiovascular Disease and Dyslipidemia: Beyond LDL
TL;DR: In patients with hypertriglyceridemia, achievement of the LDL-C goal remains the primary lipid target and the focus of lipid therapy is the reduction of cardiovascular risk rather than the modification of lipoprotein sub-fractions.