Ortrud Werner

TL;DR: The goal of the study was to establish if there was a relationship between molecular patterns and virus evolution, and the complete genome sequence of two distinct apathogenic Newcastle disease virus (NDV) strains was determined and a third genome size category, containing 15,198 nucleotides, was recognized.

TL;DR: NDV strains isolated from outbreaks during epizootics between 1992 and 1996 in Western European countries, were compared by restriction enzyme cleavage site mapping of the fusion (F) protein gene between nucleotides 334 and 1682 and by sequence analysis, revealing that NDV strains belong to two distinct genotypes.

TL;DR: 34 strains of Newcastle disease virus isolated during epizootics in the Republic of South Africa and in Mozambique between 1990 and 1995, and in Bulgaria and Turkey in 1995–1997 were identified by restriction enzyme and partial sequence analysis of the fusion (F) protein gene.

TL;DR: Rec recombinant NDV expressing an F protein with a multibasic cleavage site typical of virulent strains was able to spread efficiently in cell culture, irrespective of the size of the HN protein, and the involvement of additional virulence determinants that contribute to the pathogenicity of NDV is suggested.

TL;DR: The data suggest the introduction of three distinct H5N1 variants into the wild bird population of Germany and the source of these viruses and the exact time of introduction remain obscure.