O
Ovijit Chaudhuri
Researcher at Stanford University
Publications - 80
Citations - 13181
Ovijit Chaudhuri is an academic researcher from Stanford University. The author has contributed to research in topics: Self-healing hydrogels & Extracellular matrix. The author has an hindex of 34, co-authored 70 publications receiving 9310 citations. Previous affiliations of Ovijit Chaudhuri include University of California, San Francisco & Lawrence Berkeley National Laboratory.
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Journal ArticleDOI
Volume expansion and TRPV4 activation regulate stem cell fate in three-dimensional microenvironments.
TL;DR: The role of cell volume in regulating cell fate in 3D culture is demonstrated, and TRPV4 is identified as a molecular sensor of matrix viscoelasticity that regulates osteogenic differentiation.
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Mechanisms of Plastic Deformation in Collagen Networks Induced by Cellular Forces.
Ehsan Ban,J. Matthew Franklin,Sungmin Nam,Lucas R. Smith,Hailong Wang,Rebecca G. Wells,Ovijit Chaudhuri,Jan Liphardt,Vivek B. Shenoy +8 more
TL;DR: A coarse-grained model for plastic deformation of collagen networks that can be employed to simulate multicellular interactions in processes such as morphogenesis, cancer invasion, and fibrosis is developed.
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Cell cycle progression in confining microenvironments is regulated by a growth-responsive TRPV4-PI3K/Akt-p27Kip1 signaling axis
Sungmin Nam,Vivek K. Gupta,Hong-pyo Lee,Joanna Y. Lee,Katrina M. Wisdom,Sushama Varma,Eliott Flaum,Ciara Davis,Robert B. West,Ovijit Chaudhuri +9 more
TL;DR: In confining microenvironments, cells sense when growth is sufficient for division to proceed through a growth-responsive signaling axis mediated by SACs, and are arrested in the G0/G1 phase of the cell cycle when cultured in hydrogels that exhibit slow stress relaxation.
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Dynamic Hyaluronan Hydrogels with Temporally Modulated High Injectability and Stability Using a Biocompatible Catalyst
TL;DR: A new concept to resolve this dilemma using a biocompatible catalyst to modulate the dynamic properties of hydrogels at different time points of application to have both high injectability and high stability is presented.
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Mitotic cells generate protrusive extracellular forces to divide in three-dimensional microenvironments
Sungmin Nam,Ovijit Chaudhuri +1 more
TL;DR: By confining cells three dimensionally in hydrogels, it is shown that dividing cells generate substantial protrusive forces that deform their surroundings along the mitotic axis, clearing space for mitotic elongation, and explains how dividing cells overcome mechanical constraints in confining microenvironments.