O
Owen Jensen
Researcher at University of Colorado Denver
Publications - 2
Citations - 274
Owen Jensen is an academic researcher from University of Colorado Denver. The author has contributed to research in topics: Colitis & Innate immune system. The author has an hindex of 2, co-authored 2 publications receiving 196 citations. Previous affiliations of Owen Jensen include Anschutz Medical Campus.
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Journal ArticleDOI
Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
Viola Neudecker,Viola Neudecker,Moritz Haneklaus,Owen Jensen,Ludmila Khailova,Joanne C. Masterson,Joanne C. Masterson,Hazel Tye,Hazel Tye,Kathryn A. Biette,Kathryn A. Biette,Paul Jedlicka,Kelley S. Brodsky,Mark E. Gerich,Matthias Mack,Avril A. B. Robertson,Mark E. Cooper,Glenn T. Furuta,Glenn T. Furuta,Charles A. Dinarello,Charles A. Dinarello,Luke A. J. O'Neill,Holger K. Eltzschig,Holger K. Eltzschig,Seth L. Masters,Seth L. Masters,Eóin N. McNamee +26 more
TL;DR: It is reported that miR-223 limits intestinal inflammation by constraining the nlrp3 inflammasome in mice, revealing a previously unappreciated role in regulating the innate immune response during intestinal inflammation.
Journal ArticleDOI
Muc5ac Expression Protects the Colonic Barrier in Experimental Colitis
Kristine E. Olli,C. R. Rapp,Lauren O’Connell,Colm B. Collins,Colm B. Collins,Colm B. Collins,Eóin N. McNamee,Eóin N. McNamee,Owen Jensen,Paul Jedlicka,Kristen C. Allison,Matthew S Goldberg,Mark E. Gerich,Daniel N. Frank,Diana Ir,Charles E. Robertson,Christopher M. Evans,Carol M. Aherne,Carol M. Aherne +18 more
TL;DR: This functional study demonstrates that an alternative secreted mucin, MUC5AC/Muc5ac, is induced in colitis to protect the colonic barrier by limiting host-bacterial interaction.