Ø
Øyvind Halaas
Researcher at Norwegian University of Science and Technology
Publications - 26
Citations - 2036
Øyvind Halaas is an academic researcher from Norwegian University of Science and Technology. The author has contributed to research in topics: Tumor necrosis factor alpha & Toll-like receptor. The author has an hindex of 18, co-authored 25 publications receiving 1890 citations.
Papers
More filters
Journal ArticleDOI
Endocytic pathways regulate Toll‐like receptor 4 signaling and link innate and adaptive immunity
Harald Husebye,Øyvind Halaas,Harald Stenmark,Harald Stenmark,Gro Tunheim,Øystein Sandanger,Bjarne Bogen,Andreas Brech,Eicke Latz,Terje Espevik +9 more
TL;DR: The results show that endosomal trafficking of the LPS receptor complex is essential for signal termination and LPS‐associated antigen presentation, thus controlling both innate and adaptive immunity through TLR4.
Journal ArticleDOI
Human Toll-Like Receptor 2 Mediates Monocyte Activation by Listeria monocytogenes, But Not by Group B Streptococci or Lipopolysaccharide
Trude Helen Flo,Øyvind Halaas,Egil Lien,Egil Lien,Liv Ryan,Giuseppe Teti,Douglas T. Golenbock,Anders Sundan,Terje Espevik +8 more
TL;DR: The results show that TLR2 can function as a signaling receptor for HKLM, possibly together with CD14, but thatTLR2 is unlikely to be involved in cell activation by GBS, and this receptor does not seem to be the main transducer of LPS activation of human monocytes.
Journal ArticleDOI
Differential expression of Toll-like receptor 2 in human cells.
Trude Helen Flo,Øyvind Halaas,Sverre H. Torp,Liv Ryan,Egil Lien,Brit Dybdahl,Anders Sundan,Terje Espevik +7 more
TL;DR: Analysis of expression and regulation of the TLR2 protein in human blood cells and tissues by using two anti‐TLR2 mAbs suggests that TLR 2 protein expression in innate immune cells is differentially regulated by inflammatory mediators.
Journal ArticleDOI
Involvement of toll-like receptor (TLR) 2 and TLR4 in cell activation by mannuronic acid polymers.
Trude Helen Flo,Liv Ryan,Eicke Latz,Osamu Takeuchi,Brian G. Monks,Egil Lien,Øyvind Halaas,Shizuo Akira,Gudmund Skjåk-Bræk,Douglas T. Golenbock,Terje Espevik +10 more
TL;DR: The results suggest that both TLR2 andTLR4 are involved in cell activation by poly-M and that TLR4 may be required in primary murine macrophages.
Journal ArticleDOI
The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes
Harald Husebye,Marie Hjelmseth Aune,Jørgen Stenvik,Eivind O. Samstad,Frode Miltzow Skjeldal,Øyvind Halaas,Nadra J. Nilsen,Harald Stenmark,Harald Stenmark,Eicke Latz,Eicke Latz,Egil Lien,Egil Lien,Tom Eirik Mollnes,Oddmund Bakke,Oddmund Bakke,Terje Espevik +16 more
TL;DR: Rab11a is an important regulator of TLR4 and TRAM transport to E. coli phagosomes thereby controlling IRF3 activation from this compartment and reducing the amount of TRAM on phagosome.