F
Frode Miltzow Skjeldal
Researcher at University of Oslo
Publications - 17
Citations - 743
Frode Miltzow Skjeldal is an academic researcher from University of Oslo. The author has contributed to research in topics: Endosome & Internalization. The author has an hindex of 9, co-authored 17 publications receiving 639 citations. Previous affiliations of Frode Miltzow Skjeldal include Oslo University Hospital.
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Journal ArticleDOI
The Rab11a GTPase Controls Toll-like Receptor 4-Induced Activation of Interferon Regulatory Factor-3 on Phagosomes
Harald Husebye,Marie Hjelmseth Aune,Jørgen Stenvik,Eivind O. Samstad,Frode Miltzow Skjeldal,Øyvind Halaas,Nadra J. Nilsen,Harald Stenmark,Harald Stenmark,Eicke Latz,Eicke Latz,Egil Lien,Egil Lien,Tom Eirik Mollnes,Oddmund Bakke,Oddmund Bakke,Terje Espevik +16 more
TL;DR: Rab11a is an important regulator of TLR4 and TRAM transport to E. coli phagosomes thereby controlling IRF3 activation from this compartment and reducing the amount of TRAM on phagosome.
Journal ArticleDOI
Cellular trafficking of lipoteichoic acid and Toll-like receptor 2 in relation to signaling: role of CD14 and CD36
Nadra J. Nilsen,Susanne Deininger,Unni Nonstad,Frode Miltzow Skjeldal,Harald Husebye,Dmitrii G. Rodionov,Sonja von Aulock,Thomas Hartung,Egil Lien,Oddmund Bakke,Terje Espevik +10 more
TL;DR: The results suggest that LTA signaling preferentially occurs at the plasma membrane, is independent of internalization, and is facilitated by CD36 and CD14 as coreceptors for TLR2.
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Nanoparticles as drug delivery system against tuberculosis in zebrafish embryos: direct visualization and treatment.
Federico Fenaroli,David Westmoreland,Jørgen Benjaminsen,Terje R Selnes Kolstad,Frode Miltzow Skjeldal,Annemarie H. Meijer,Michiel van der Vaart,Lilia S. Ulanova,Norbert Roos,Bo Nyström,Jon Hildahl,Gareth Griffiths +11 more
TL;DR: The results argue that zebrafish embryos offer a powerful system for monitoring NPs in vivo and rationalize why NP therapy was so effective against Mtb in earlier studies; bacteria and NPs share the same cellular niche.
Journal ArticleDOI
The fusion of early endosomes induces molecular-motor-driven tubule formation and fission
Frode Miltzow Skjeldal,Sten Strunze,Trygve Bergeland,Even Walseng,Tone F. Gregers,Oddmund Bakke,Oddmund Bakke +6 more
TL;DR: The results show that fusion of endosomes is a rapid process that destabilizes the membrane and instantly induces molecular-motor-driven tubule formation and fission.
Journal ArticleDOI
Toll-Like Receptor 2 (P631H) Mutant Impairs Membrane Internalization and is a Dominant Negative Allele
G. E. Etokebe,Frode Miltzow Skjeldal,Nadra J. Nilsen,Dmitrii G. Rodionov,Jelena Knezevic,Ljiljana Bulat-Kardum,Ljiljana Bulat-Kardum,Terje Espevik,Oddmund Bakke,Zlatko Dembic +9 more
TL;DR: The data, in combination with a report by others show that the TLR2‐P631H allele could be associated with protection to meningococcal meningitis, suggest that by dominantly inhibiting the response of cells important in the immune response this mutant might confer either protection or susceptibility toMeningitis or tuberculosis, respectively.