P. A. C. Maple

TL;DR: There were geographical patterns of resistance: MRSA from the UK and Australia were predominantly resistant to trimethoprim, whereas many strains from centres in Europe and the USA were sensitive.

TL;DR: Seroprevalence of standardized anti-PT antibody was determined in six Western European countries between 1994 and 1998 and related to historical surveillance and vaccine programme data, finding recent infection was significantly more likely in adolescents and adults in high-coverage countries.

TL;DR: Seven countries in Western Europe collected large, representative serum banks across the entire age range and tested them for diphtheria anti-toxin, showing large differences in the proportion of adults with insufficient levels of protection amongst different countries.

TL;DR: A standardisation process was developed in order to compare and harmonize serological results of pertussis toxin (PT) antibody measurements performed by laboratories using different technical procedures for detection, with a particular emphasis on achieving standardisation of high titre results that would allow epidemiological evaluations based on the estimation of the incidence of recent infections rather than on the traditional approach of determining the population immunity profile.

TL;DR: The results suggest that booster immunisation of adults is necessary to increase herd immunity of the adult population and show a significant trend of decreasing immunity with increasing age.