P
P. M. Taylor
Researcher at National Institute for Medical Research
Publications - 20
Citations - 773
P. M. Taylor is an academic researcher from National Institute for Medical Research. The author has contributed to research in topics: Cytotoxic T cell & Antigen. The author has an hindex of 13, co-authored 20 publications receiving 769 citations.
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Class I MHC molecules rather than other mouse genes dictate influenza epitope recognition by cytotoxic T cells.
TL;DR: Tc cell recognition of NP peptide 147–161 is entirely dictated by expression of Kd and not by other B10 or OH background genes of congenic mice, suggesting that antigen and class I MHC interact for Tc recognition.
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Activation of complement, the induction of antibodies to the surface of nematodes and the effect of these factors and cells on worm survival in vitro.
TL;DR: This report describes the effect on various stages in the life cycle of the nematodes T. spiralis and N. brasiliensis of complement, antibodies from rats infected with these parasites and several different cell types.
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Expression of marine H-2Kb histocompatibility antigen in cells transformed with cloned H-2 genes
Andrew L. Mellor,L. Golden,E. H. Weiss,H. Bullman,J. Hurst,Elizabeth M. Simpson,R. James,Alain Townsend,P. M. Taylor,Walter Schmidt,J. Ferluga,L. Leben,M. Santamaria,G. Atfield,Hilliard Festenstein,Richard A. Flavell +15 more
TL;DR: Results show that expression of the H–2Kb gene product on the L-cell surface is sufficient to make it a target for specific T-cell killing.
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The in‐vitro interaction of eosinophils, neutrophils, macrophages and mast cells with nematode surfaces in the presence of complement or antibodies
TL;DR: The adherence in vitro of leucocytes to the surface of various stages in the life cycle of T. spiralis and N. brasiliensis in the presence of serum was examined and a positive NBT reaction occurred only with neutrophils and not with eosinophils, mast cells or macrcphages.
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Immune response to stage-specific surface antigens of the parasitic nematode Trichinella spiralis.
TL;DR: The surface proteins of T. spiralis used in this study are antigenically stage specific and could be targets for the stage-specific, antibody- dependent eosinophil-mediated destruction of this parasite, known to occur in vitro.