P
P. Naresh Kumar
Researcher at Scripps Research Institute
Publications - 1
Citations - 464
P. Naresh Kumar is an academic researcher from Scripps Research Institute. The author has contributed to research in topics: Cellular differentiation & Receptor. The author has an hindex of 1, co-authored 1 publications receiving 412 citations.
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Suppression of TH17 Differentiation and Autoimmunity by a Synthetic ROR Ligand
Laura A. Solt,P. Naresh Kumar,Philippe Nuhant,Yongjun Wang,Janelle L. Lauer,J. J. Liu,Monica A. Istrate,Theodore M. Kamenecka,William R. Roush,Dusica Vidovic,Dusica Vidovic,Stephan C. Schürer,Stephan C. Schürer,Jihong Xu,Gail Wagoner,Paul D. Drew,Patrick R. Griffin,Thomas P. Burris +17 more
TL;DR: The data demonstrate the feasibility of targeting the orphan receptors RORα and RORγt to inhibit specifically TH17 cell differentiation and function, and indicate that this novel class of compound has potential utility in the treatment of autoimmune diseases.