P. Profice

TL;DR: The differential effect of scopolamine on motor responses evoked by magnetic and electrical stimulation of the motor cortex and the selective effect on somatosensory inhibition demonstrate that muscarinic blockade modifies the excitability of specific cortical networks in the human motor cortex.

TL;DR: The findings suggest that this method can be used as a noninvasive test of cholinergic pathways in AD and Administration of a single oral dose of rivastigmine improved afferent inhibition in a subgroup of six patients.

TL;DR: It is suggested that the enhancement of human motor cortex excitability to transcranial magnetic stimulation is the effect of an increase in glutamatergic transmission at non‐NMDA receptors similar to that described in experimental studies.

TL;DR: Unexpectedly, the descending volleys evoked by AP stimulation often had slightly different peak latencies and/or longer duration than those seen after PA stimulation, suggesting that AP stimulation does not simply activate a subset of the sites activated by PA stimulation.

TL;DR: It is concluded that ICF occurs because either the conditioning stimulus has a (thus far undetected) effect on spinal cord excitability that increases its response to the same amplitude test volley or it can alter the composition (but not the amplitude) of the descending volleys set up by the test stimulus such that a larger proportion of the activity is destined for the target muscle.