P
Päivi Lehtovaara
Researcher at University of Helsinki
Publications - 34
Citations - 2799
Päivi Lehtovaara is an academic researcher from University of Helsinki. The author has contributed to research in topics: Trichoderma reesei & Gene. The author has an hindex of 22, co-authored 34 publications receiving 2774 citations.
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Journal ArticleDOI
Homologous domains in Trichoderma reesei cellulolytic enzymes: gene sequence and expression of cellobiohydrolase II.
TL;DR: A short region of extensive homology is found in all Trichoderma cellulases characterized so far, suggesting that this region is important for cellulose hydrolysis.
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Homology between cellulase genes of Trichoderma reesei: complete nucleotide sequence of the endoglucanase I gene
TL;DR: Cloned and sequenced the gene and the full-length cDNA coding for the major endoglucanase EG-I, and compared this to the cbh1 gene sequence to clarify the relationship between the EG and CBH classes of cellulases suggest that the two enzymes have arisen from a common ancestor by gene duplication.
Journal ArticleDOI
EGIII, a new endoglucanase from Trichoderma reesei: the characterization of both gene and enzyme
Markku Saloheimo,Päivi Lehtovaara,Merja Penttilä,TT Teeri,Jerry Ståhlberg,Gunnar Johansson,Göran Pettersson,Marc Claeyssens,Peter Tomme,J. Knowles +9 more
TL;DR: Comparison of the fungal cellulase structures has led to re-evaluation of hypotheses concerning the localization of the active sites, and all the four T. reesei cellulases share two common, adjacent sequence domains, which apparently can be removed by proteolysis.
Journal ArticleDOI
Cellulase families and their genes
TL;DR: Cellulases play a central role in the recycling of lignocellulose and molecular biology is now helping to unravel the complex enzymology of cellulose hydrolysis and giving information that will be of use both for the improvement of existing processes and for the development of completely new areas.
Journal ArticleDOI
Secretion of interferon by Bacillus subtilis.
Ilkka Palva,Päivi Lehtovaara,Leevi Kääriäinen,Mervi Sibakov,Kari Cantell,Catherine H. Schein,Kiyoko Kashiwagi,Charles Weissmann +7 more
TL;DR: Bacillus subtilis was transformed with a hybrid gene in which the sequence encoding the alpha-amylase signal peptide was joined by a linker to the sequence encode mature human interferon alpha 2(IFN-alpha 2).