P
Palchamy Elango
Researcher at National Institutes of Health
Publications - 11
Citations - 598
Palchamy Elango is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Vitamin D and neurology & Arterial stiffness. The author has an hindex of 6, co-authored 10 publications receiving 428 citations.
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Journal ArticleDOI
Longitudinal Trajectories of Arterial Stiffness and the Role of Blood Pressure The Baltimore Longitudinal Study of Aging
Majd AlGhatrif,James B. Strait,Christopher H. Morrell,Marco Canepa,Jeanette G. Wright,Palchamy Elango,Angelo Scuteri,Samer S. Najjar,Luigi Ferrucci,Edward G. Lakatta +9 more
TL;DR: In this paper, the authors collected 2 to 9 serial measures of PWV in 354 men and 423 women of the Baltimore Longitudinal Study of Aging, who were 21 to 94 years of age and free of clinically significant cardiovascular disease.
Journal ArticleDOI
Arterial stiffness and vitamin D levels: the Baltimore longitudinal study of aging.
Francesco Giallauria,Yuri Milaneschi,Yuri Milaneschi,Toshiko Tanaka,Marcello Maggio,Marco Canepa,Palchamy Elango,Carlo Vigorito,Edward G. Lakatta,Luigi Ferrucci,James B. Strait +10 more
TL;DR: Vitamin D levels are inversely associated with increased arterial stiffness in a normative aging population, irrespective of traditional risk factor burden.
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A roadmap to build a phenotypic metric of ageing: insights from the Baltimore Longitudinal Study of Aging.
Pei-Lun Kuo,Pei-Lun Kuo,Jennifer A. Schrack,Jennifer A. Schrack,Michelle Shardell,Morgan E. Levine,Ann Zenobia Moore,Yang An,Palchamy Elango,Ajoy C. Karikkineth,Toshiko Tanaka,R. de Cabo,Linda Zukley,Majd AlGhatrif,Chee Wei Chia,Eleanor M. Simonsick,Josephine M. Egan,Susan M. Resnick,Luigi Ferrucci +18 more
TL;DR: A conceptual framework to identify metrics of ageing that may capture the hierarchical and temporal relationships between functional ageing, phenotypic ageing and biological ageing based on four hypothesized domains: body composition, energy regulation, homeostatic mechanisms and neurodegeneration/neuroplasticity is proposed.
Journal ArticleDOI
Midlife anticholinergic drug use, risk of Alzheimer's disease, and brain atrophy in community-dwelling older adults.
Yi-Fang Chuang,Yi-Fang Chuang,Yi-Fang Chuang,Palchamy Elango,Christopher E. Gonzalez,Madhav Thambisetty +5 more
TL;DR: This work examined how long‐term anticholinergic drug use beginning at midlife affects risk of Alzheimer's disease and rates of brain atrophy in cognitively normal older adults.
Journal ArticleDOI
Telomere Shortening, Inflammatory Cytokines, and Anti-Cytomegalovirus Antibody Follow Distinct Age-Associated Trajectories in Humans.
Ana Lustig,Hans B. Liu,E. Jeffrey Metter,Yang An,Melissa A. Swaby,Palchamy Elango,Luigi Ferrucci,Richard J. Hodes,Nan-ping Weng +8 more
TL;DR: The findings reveal that age-related trajectories of telomere attrition, elevated circulating inflammatory cytokines, and anti-CMV IgG are independent and that aging individuals do not show a uniform pattern of change in these variables.