Pamela Liyala

TL;DR: From the ethyl acetate extract of the stem bark of Erythrina abyssinica, a new chalcone, 2',3,4,4'-tetrahydroxy-5-prenylchalcone (trivial name 5- prenylbutein) and a new flavanone along with known flavonoids have been isolated as the anti-plasmodial principles.

TL;DR: The dichloromethane extract of the stem bark of Millettia usaramensis subspecies usaramense showed anti-plasmodial activity against the chloroquine sensitive (D6) andchloroquine resistant (W2) strains of Plasmodium falciparum.

TL;DR: The crude extract and the flavonoids and isoflavonoids obtained from the roots of this plant showed antiplasmodial activities.

TL;DR: Chromatographic separation of the acetone extract of the root bark afforded a new is oflavone, 7-hydroxy-4'-methoxy-3'-prenylisoflavone (trivial name 5-deoxy-2'-3'- prenylbiochanin A) along with known isoflavonoids as the antiplasmodial principles.

TL;DR: In this article, the drug resistance profiles of Plasmodium falciparum isolated from four regions in Kenya were analyzed for drug resistance profile and observed variability in resistance to a broad range of antimalarial drugs across Kenya as determined from in vitro drug susceptibility screening and genotyping analysis.