P
Pamela S. Douglas
Researcher at Harvard University
Publications - 55
Citations - 4641
Pamela S. Douglas is an academic researcher from Harvard University. The author has contributed to research in topics: Diastole & Atrial fibrillation. The author has an hindex of 33, co-authored 55 publications receiving 4510 citations. Previous affiliations of Pamela S. Douglas include Dana Corporation & Cleveland Clinic.
Papers
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Journal ArticleDOI
The conserved phosphoinositide 3-kinase pathway determines heart size in mice
Tetsuo Shioi,Peter M. Kang,Pamela S. Douglas,James Hampe,Claudine M. Yballe,Joel A. Lawitts,Lewis C. Cantley,Seigo Izumo +7 more
TL;DR: The PI3K pathway is necessary and sufficient to promote organ growth in mammals and was associated with comparable increase or decrease in myocyte size in transgenic mice.
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Impaired left atrial mechanical function after cardioversion: Relation to the duration of atrial fibrillation
Warren J. Manning,David I. Silverman,Sarah E. Katz,Marilyn F. Riley,Patricia C. Come,Rosalie M. Doherty,Jiyl T. Munson,Pamela S. Douglas +7 more
TL;DR: Recovery of left atrial mechanical function is related to the duration of atrial fibrillation before cardioversion, and these findings have important implications for assessing the early hemodynamic benefit of successful cardioversion.
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Transesophageal echocardiographically facilitated early cardioversion from atrial fibrillation using short-term anticoagulation: final results of a prospective 4.5-year study
TL;DR: This large prospective and consecutive study of patients undergoing transesophageal echocardiographically facilitated early cardioversion in conjunction with short-term anticoagulation validates the safety of this strategy.
Journal ArticleDOI
Cardiac fatigue after prolonged exercise.
TL;DR: The stress-shortening relationship was displaced downward at race finish, but returned toward baseline after 1 day of recovery, despite a persistent reduction in cavity size, which suggests that the decrease in shortening was due to impaired contractility as well as altered preload.
Journal ArticleDOI
Cardiac troponin T and I, electrocardiographic wall motion analyses, and ejection fractions in athletes participating in the Hawaii Ironman Triathlon
Nader Rifai,Nader Rifai,Pamela S. Douglas,Pamela S. Douglas,Pamela S. Douglas,Mary L. O'Toole,Eric B. Rimm,Geoffrey S. Ginsburg,Geoffrey S. Ginsburg,Geoffrey S. Ginsburg +9 more
TL;DR: Ultraendurance exercise may cause myocardial damage as indicated by biochemical cardiac-specific markers and echocardiography and ejection fraction decreased by an average of 24% after the race (p <0.002).