P
Paola Bovolenta
Researcher at Spanish National Research Council
Publications - 157
Citations - 9687
Paola Bovolenta is an academic researcher from Spanish National Research Council. The author has contributed to research in topics: Retina & Eye development. The author has an hindex of 56, co-authored 152 publications receiving 9005 citations. Previous affiliations of Paola Bovolenta include Autonomous University of Madrid & Columbia University.
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Journal ArticleDOI
Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease.
Paola Bovolenta,Pilar Esteve,Pilar Esteve,José María García Ruiz,José María García Ruiz,Elsa Cisneros,Elsa Cisneros,Javier Lopez-Rios +7 more
TL;DR: These studies indicate that SFRPs are not merely Wnt-binding proteins, but can also antagonise one another's activity, bind to Fz receptors and influence axon guidance, interfere with BMP signalling by acting as proteinase inhibitors, and interact with other receptors or matrix molecules.
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Growth cone morphology varies with position in the developing mouse visual pathway from retina to first targets
Paola Bovolenta,Carol Ann Mason +1 more
TL;DR: Results demonstrate that in this single pathway from origin to targets, growth cone morphology varies systematically with position along the visual pathway.
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Otx genes are required for tissue specification in the developing eye
Juan Ramón Martínez-Morales,Massimo Signore,Massimo Signore,Dario Acampora,Antonio Simeone,Paola Bovolenta +5 more
TL;DR: A model is proposed in which Otx gene products are required for the determination and differentiation of the pigment epithelium, co-operating with other eye patterning genes in the determination of the specialised tissues that will constitute the mature vertebrate eye.
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Eye development: a view from the retina pigmented epithelium.
TL;DR: Many recent findings are outlined that suggest that a limited number of transcription factors, including Otx2, Mitf and Pax6 and a few signalling cascades, are the elements required for the onset of RPE specification in vertebrates.
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Sonic hedgehog in CNS development: one signal, multiple outputs.
Elisa Martí,Paola Bovolenta +1 more
TL;DR: A more precise understanding of the molecular mechanisms that underlie the different responses to SHH signalling is the next step in the study of this molecule and its role in the regulation of neural development.