P
Paola Frati
Researcher at Sapienza University of Rome
Publications - 195
Citations - 2921
Paola Frati is an academic researcher from Sapienza University of Rome. The author has contributed to research in topics: Medicine & Health care. The author has an hindex of 23, co-authored 159 publications receiving 1916 citations. Previous affiliations of Paola Frati include American Board of Legal Medicine & University of Sannio.
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Autopsy findings in COVID-19-related deaths: a literature review
Aniello Maiese,Alice Chiara Manetti,Raffaele La Russa,Marco Di Paolo,Emanuela Turillazzi,Paola Frati,Vittorio Fineschi +6 more
TL;DR: It appears that there is a high incidence of deep vein thrombosis and pulmonary embolism among COVID-19 decedents, suggesting endothelial involvement, but more studies are needed.
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Anabolic androgenic steroid (AAS) related deaths: Autoptic, histopathological and toxicological findings
TL;DR: The aim of this review is to focus on deaths related to AAS abuse, trying to evaluate the autoptic, histopathological and toxicological findings in order to investigate the pathophysiological mechanism that underlines this type of death, which is still obscure in several aspects.
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Diffuse Axonal Injury and Oxidative Stress: A Comprehensive Review.
Alessandro Frati,Daniela Cerretani,Anna Ida Fiaschi,Paola Frati,Vittorio Gatto,Raffaele La Russa,Alessandro Pesce,Enrica Pinchi,Alessandro Santurro,Flavia Fraschetti,Vittorio Fineschi +10 more
TL;DR: Following TBI, axonal degeneration has been identified as a progressive process that starts with disrupted axonal transport causing axonal swelling, followed by secondary axonal disconnection and Wallerian degeneration, and studies support the role of an altered axonal calcium homeostasis as a mechanism in the secondary damage of axon, and suggest that calcium channel blocker can alleviate the secondaryDamage.
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Clinical Applications of Personalized Medicine: A New Paradigm and Challenge
Mariantonia Di Sanzo,Luigi Cipolloni,Marina Borro,Raffaele La Russa,Alessandro Santurro,Matteo Scopetti,Maurizio Simmaco,Paola Frati +7 more
TL;DR: The purpose of this study is to evaluate the personalized medicine about its indications and benefits, actual clinical applications and future perspectives as well as its issues and health care implications.
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Male breast cancer: genetics, epigenetics, and ethical aspects
Piera Rizzolo,Valentina Silvestri,Stefania Tommasi,Rosamaria Pinto,Katia Danza,Mario Falchetti,Matteo Gulino,Paola Frati,Laura Ottini +8 more
TL;DR: Overall, much still needs to be learned about MBC and, because of its rarity, the main effort is to develop large consortia for moving forward in understanding and improving the management of MBC patients on a perspective of gender medicine.