Paolo Perrotta

TL;DR: It is concluded that, in order to avoid artifacts and exclude the several sources of bias that may influence the analysis, an optimal method should comprise a careful preprocessing of the images, be based on multimodal, complementary data, take into account spatial information about the lesions and correct for false positives.

TL;DR: This study provides a useful new neuroimaging tool to characterize ALS‐related neurodegenerative processes by means of CST profile, and demonstrated that specific microstructural changes in the upper part of the brainstem might be considered as a valid biomarker.

TL;DR: DTI tractography metrics provided by TRACULA perfectly agree with those previously reported in several post-mortem and DTI studies, thus demonstrating the accuracy of this method in characterizing the microstructural changes occurring in ALS.

TL;DR: The MRPI appears to be a more reliable imaging measurement compared with midbrain/pons values for differentiating PSP from PD and controls in an elderly population.

TL;DR: The presence of the cerebellar signs drastically impacts on the neurofunctional networks underlying working memory in MS, offering new insights into the pathophysiological mechanisms of cognition in MS.