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Alessia Sarica

Researcher at Magna Græcia University

Publications -  63
Citations -  2426

Alessia Sarica is an academic researcher from Magna Græcia University. The author has contributed to research in topics: Medicine & Tractography. The author has an hindex of 15, co-authored 48 publications receiving 1642 citations. Previous affiliations of Alessia Sarica include National Research Council.

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The challenge of mapping the human connectome based on diffusion tractography

Klaus H. Maier-Hein, +76 more
TL;DR: The encouraging finding that most state-of-the-art algorithms produce tractograms containing 90% of the ground truth bundles (to at least some extent) is reported, however, the same tractograms contain many more invalid than valid bundles, and half of these invalid bundles occur systematically across research groups.
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Random Forest Algorithm for the Classification of Neuroimaging Data in Alzheimer's Disease: A Systematic Review.

TL;DR: The lesson learnt suggest that when RF was applied on multi-modal data for prediction of Alzheimer's disease (AD) conversion from the Mild Cognitive Impairment (MCI), it produces one of the best accuracies to date.
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Standardized evaluation of algorithms for computer-aided diagnosis of dementia based on structural MRI: The CADDementia challenge

TL;DR: A grand challenge to objectively compare algorithms based on a clinically representative multi-center data set of three diagnostic groups, finding the best performances were achieved using feature extraction based on voxel-based morphometry or a combination of features that included volume, cortical thickness, shape and intensity.
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Autism-associated 16p11.2 microdeletion impairs prefrontal functional connectivity in mouse and human

TL;DR: In this paper, the authors used resting state functional MRI data from the Simons Variation in Individuals Project (VIP) database to identify variants that increase risk for neurodevelopmental disorders and suggest that deletion in 16p11.2 may lead to impaired socio-cognitive function via dysregulation of prefrontal connectivity.
Posted ContentDOI

Tractography-based connectomes are dominated by false-positive connections

Klaus H. Maier-Hein, +76 more
- 07 Nov 2016 - 
TL;DR: The results demonstrate fundamental ambiguities inherent to tract reconstruction methods based on diffusion orientation information, with critical consequences for the approach of diffusion tractography in particular and human connectivity studies in general.