Andrea Cherubini

TL;DR: Parkinson-associated physiopathological modifications were characterized in six subcortical structures by simultaneously measuring quantitative magnetic resonance parameters sensitive to complementary tissue characteristics, demonstrating that multimodal magnetic resonance imaging of sub cortical grey matter structures is useful for the evaluation of Parkinson's disease and, possibly, of other subcortsical pathologies.

TL;DR: In the largest neuroimaging study to date, Whelan and colleagues report robust structural alterations across and within epilepsy syndromes, including shared volume loss in the thalamus, and widespread cortical thickness differences.

TL;DR: The statistical analyses highlighted characteristic patterns of variation for the measurements in the various structures evaluated in this study, which contribute in establishing a baseline for comparison with pathological changes in the basal ganglia and thalamus.

TL;DR: Callosal changes are already present in patients with amnestic mild cognitive impairment (MCI) and mild Alzheimer disease (AD) and a retrogenesis process in the anterior callosal subregions of the corpus callosum is suggested to be responsible.

TL;DR: It is concluded that, in order to avoid artifacts and exclude the several sources of bias that may influence the analysis, an optimal method should comprise a careful preprocessing of the images, be based on multimodal, complementary data, take into account spatial information about the lesions and correct for false positives.