P
Paolo Tortora
Researcher at University of Milano-Bicocca
Publications - 120
Citations - 4322
Paolo Tortora is an academic researcher from University of Milano-Bicocca. The author has contributed to research in topics: Sulfolobus solfataricus & Polynucleotide phosphorylase. The author has an hindex of 35, co-authored 118 publications receiving 4015 citations. Previous affiliations of Paolo Tortora include Sapienza University of Rome & University of Milan.
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Journal ArticleDOI
Direct activation of cardiac pacemaker channels by intracellular cyclic AMP
Dario DiFrancesco,Paolo Tortora +1 more
TL;DR: This work finds that cAMP activates if by a mechanism independent of phosphorylation, involving a direct interaction with the channels at their cytoplasmic side, the first evidence of an ion channel whose gating is dually regulated by voltage and direct cAMP binding.
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Sequence Stratigraphy and Depositional Setting of the Tiber Delta: Integration of High-resolution Seismics, Well Logs, and Archeological Data
TL;DR: Using archeological evidence, radiocarbon data, well logs, and high-resolution seismic profiles, the authors applied sequence-stratigraphic analysis to sediments deposited during the last glacio-eustatic cycle on the Tyrrhenian continental margin embracing the Tiber River months.
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Physical stratigraphy and sedimentology of the Late Pleistocene‐Holocene Tiber Delta depositional sequence
TL;DR: The Tiber Delta is a Late Pleistocene-Holocene sedimentary succession and constitutes an incomplete high-frequency depositional sequence (4th or 5th order), which developed from the last postglacial rise in sea level to the present stillstand as discussed by the authors.
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Biotechnological approaches toward nanoparticle biofunctionalization
TL;DR: An overview of recent advances in the immobilization of targeting proteins is provided, focusing on methods to control ligand orientation and density, and criteria for nanoparticle design and development required to achieve enhanced receptor-targeting efficiency are highlighted.
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Protein nanocages for self-triggered nuclear delivery of DNA-targeted chemotherapeutics in Cancer Cells
Michela Bellini,Serena Mazzucchelli,Elisabetta Galbiati,Silvia Sommaruga,Luisa Fiandra,Marta Truffi,Maria Antonietta Rizzuto,Miriam Colombo,Paolo Tortora,Fabio Corsi,Davide Prosperi +10 more
TL;DR: The results from confocal microscopy and DNA damage assays proved that loading of doxorubicin in HFn nanoparticles increased the nuclear delivery of the drug, thus enhancing doxorbicin efficacy, and was reliable and straightforward providing an antiproliferative effect with high reproducibility.