Luisa Fiandra

TL;DR: The structure and functions of ferritin nanocages are described, and an overview about the nanotechnological approaches implemented for applying them to cancer diagnosis and treatment is provided.

TL;DR: The results highlight the importance of precisely controlling the ligand density on the nanoparticle surface for optimizing active targeting, and that less antibodies can exhibit more effect.

TL;DR: The results from confocal microscopy and DNA damage assays proved that loading of doxorubicin in HFn nanoparticles increased the nuclear delivery of the drug, thus enhancing doxorbicin efficacy, and was reliable and straightforward providing an antiproliferative effect with high reproducibility.

TL;DR: Evidence is provided that active targeting plays an important role in determining the biological activity of the nanoconstruct in the case of multifunctional nanoparticles functionalized with TZ or with alternative lower molecular weight variants of the monoclonal antibody.

TL;DR: Results indicate that AcMNPV-ChiA may offer interesting new opportunities for pest control, and show both exo- and endo-chitinase activities.