P
Pascale Winckler
Researcher at University of Burgundy
Publications - 26
Citations - 571
Pascale Winckler is an academic researcher from University of Burgundy. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 8, co-authored 20 publications receiving 386 citations. Previous affiliations of Pascale Winckler include French Institute of Health and Medical Research.
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Journal ArticleDOI
Visualization of RNA-Quadruplexes in Live Cells
Aurélien Laguerre,Kyle R. Hukezalie,Pascale Winckler,Fares Katranji,Gaëtan Chanteloup,Marc Pirrotta,Jean-Marie Perrier-Cornet,Judy M. Y. Wong,David Monchaud +8 more
TL;DR: N-TASQ is reported on, a next-generation quadruplex ligand that acts as a multiphoton turn-on fluorescent probe that enables the direct detection of RNA-quadruplexes in untreated cells (no fixation, permeabilization or mounting steps), thus offering a unique, unbiased visualization of quadruplexe in live cells.
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Biobased Composite Films from Chitosan and Lignin: Antioxidant Activity Related to Structure and Moisture
Kevin Crouvisier-Urion,Philippe R. Bodart,Pascale Winckler,Jésus Raya,Régis D. Gougeon,Philippe Cayot,Sandra Domenek,Frédéric Debeaufort,Thomas Karbowiak +8 more
TL;DR: In this paper, composite films based on chitosan and lignin biopolymers were investigated for their mechanical, barrier, surface, and antioxidant properties and linked to an extensive microscopic analysis of their external and internal structure.
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Impact of the homogenization process on the structure and antioxidant properties of chitosan-lignin composite films.
Kevin Crouvisier-Urion,Aurélie Lagorce-Tachon,Camille Lauquin,Pascale Winckler,Wirongrong Tongdeesoontorn,Sandra Domenek,Frédéric Debeaufort,Thomas Karbowiak +7 more
TL;DR: No significant difference in the radical scavenging activity was noticeable, neither after HS nor HP processing, however, a migration of lignin residues from the film to the extraction medium was noticed, particularly for HP process.
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Surviving the heat: heterogeneity of response in Saccharomyces cerevisiae provides insight into thermal damage to the membrane
Stéphane Guyot,Patrick Gervais,Michael Young,Pascale Winckler,Jennifer Dumont,Hazel M. Davey +5 more
TL;DR: It is shown that the impact of exogenous nutrients on acquisition of thermal resistance differs between strains, and that plasma membrane permeability and potential are key factors involved in cell survival, but thermal resistance is not related to homeoviscous adaptation of the plasma membrane.
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Physico-chemical state influences in vitro release profile of curcumin from pectin beads.
TL;DR: Physico-chemical properties of encapsulated curcumin such as its solubility, physical state, tautomeric forms and encapsulation efficiency as well as encapsulation yield were characterized and in vitro dissolution ofCurcumin from beads displayed different kinetic profiles according to bead composition due to different matrix network.