P
Patrik Stolt
Researcher at Karolinska Institutet
Publications - 7
Citations - 3133
Patrik Stolt is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Odds ratio & Arthritis. The author has an hindex of 7, co-authored 7 publications receiving 2939 citations. Previous affiliations of Patrik Stolt include Intertek & Innlandet Hospital Trust.
Papers
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Journal ArticleDOI
A new model for an etiology of rheumatoid arthritis: smoking may trigger HLA-DR (shared epitope)-restricted immune reactions to autoantigens modified by citrullination.
Lars Klareskog,Patrik Stolt,Karin Lundberg,Henrik Källberg,Camilla Bengtsson,Johan Grunewald,Johan Rönnelid,Helena Erlandsson Harris,Ann-Kristin Ulfgren,Solbritt Rantapää-Dahlqvist,Anders Eklund,Leonid Padyukov,Lars Alfredsson +12 more
TL;DR: An etiology involving a specific genotype, an environmental provocation, and the induction of specific autoimmunity are suggested, all restricted to a distinct subset of RA.
Journal ArticleDOI
A gene-environment interaction between smoking and shared epitope genes in HLA-DR provides a high risk of seropositive rheumatoid arthritis
TL;DR: The disease risk of RF-seropositive RA associated with one of the classic genetic risk factors for immune-mediated diseases (the SE of HLA-DR) is strongly influenced by the presence of an environmental factor (smoking) in the population at risk.
Journal ArticleDOI
Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases
Patrik Stolt,Camilla Bengtsson,B Nordmark,Sverker Lindblad,Ingrid E. Lundberg,Lars Klareskog,Lars Alfredsson +6 more
TL;DR: Smokers of both sexes have an increased risk of developing seropositive, but not seronegative, RA, which occurs after a long duration, but merely a moderate intensity, of smoking and may remain for several years after smoking cessation.
Journal ArticleDOI
Silica exposure is associated with increased risk of developing rheumatoid arthritis: results from the Swedish EIRA study
Patrik Stolt,Henrik Källberg,Ingvar Lundberg,Bengt Sjögren,Lars Klareskog,Lars Alfredsson,Lars Alfredsson +6 more
TL;DR: The joint effects of silica exposure and smoking were compatible with synergy between these two exposures in the development of rheumatoid arthritis but this was not conclusive.
Journal ArticleDOI
Silica exposure among male current smokers is associated with a high risk of developing ACPA-positive rheumatoid arthritis
Patrik Stolt,Abqariyah Yahya,Camilla Bengtsson,Henrik Källberg,Johan Rönnelid,Ingvar Lundberg,Lars Klareskog,Lars Alfredsson +7 more
TL;DR: The results suggest that different inhalation exposures may interact in the aetiology of ACPA-positive RA, and that silica exposure combined with smoking among men is associated with an increased risk of developing ACPA -positive RA.