Patrizia Carrarelli

TL;DR: The upregulated autophagic process observed in ovarian endometriomas can be regarded as an integral part of Endometriosis pathogenesis, possibly contributing to survival ofendometriotic cells in ectopic sites and to lesion maintenance.

TL;DR: Adenomyotic nodules are novel site of expression of inflammatory and neurogenic factors, probably involved in the pathogenesis of adenomyosis, which is a uterine disorder characterized by dysmenorrhea, dyspareunia, abnormal uterine bleeding, and infertility.

TL;DR: A and M act on human HM and are regulated by steroids and there is an increase of A, M, FLRG, and Cripto expression in HL, and A and M increased Smad7 expression in HM explants.

TL;DR: Endometrium from women with endometriosis showed higher AMH and AMHRII mRNA levels than control women, with no significant differences between proliferative and secretory phases, which suggests a possible involvement of AMH in endometRIosis.

TL;DR: The overall data point out that the heterogeneity of the disease reflects differences in expression levels of genes associated with hypoxia and angiogenesis, suggesting that such conditions may have an active role in the development of the Disease.