Paul Edward Bowden

TL;DR: This revised nomenclature accommodates functional genes and pseudogenes, and although designed specifically for the full complement of human keratins, it offers the flexibility needed to incorporate additional keratin proteins from other mammalian species.

TL;DR: Immunohistochemistry with specific anti-keratin monoclonal and polyclonal antibodies was used to examine AW in normal healthy volunteers and found that keratinocytes populated the wound bed below the scab by migration, supported by keratinocyte proliferation in the surrounding epidermis both at and adjacent to the wound edge.

TL;DR: The transition from anagen to telogen is marked by downregulation of hair cortical specific keratins and the appearance of hK14 in the epithelial sac to which the telogen hair fiber is anchored.

TL;DR: Eight novel keratin mutations that cause epidermolytic hyperkeratosis with differing phenotypes are found, suggesting that genotype-phenotype relationships in epidermite are complex and do not solely depend on the type of mutation but also depend on interactions between the behavior of the mutant protein and the cellular environment.

TL;DR: EBS is a mechanobullous skin fragility disease characterized by cytolysis of basal keratinocytes and intraepidermal blistering often caused by mutations in keratin genes.