Paul L. Wolf

TL;DR: An increase in the level of HIF-1alpha is an early response to myocardial ischemia or infarction, which defines, at a molecular level, one of the first adaptations of human myocardium to a deprivation of blood.

TL;DR: There is an association between a history of spontaneous ventricular arrhythmia and an increased density of sympathetic nerves in patients with severe heart failure, and these findings suggest that abnormally increased postinjury sympathetic nerve density may be in part responsible for the occurrence of ventricular tachycardia and sudden cardiac death in these patients.

TL;DR: It is concluded that chronic myocardial infarction results in sympathetic nerve sprouting and creates a high-yield model of spontaneous VT, VF, and SCD in chronic MI.

TL;DR: All forms of pulmonary hypertension are linked by defects in the signaling pathway involving angiopoietin-1, TIE2, BMPR1A, and BMPR2 and consequently identify specific molecular targets for therapeutic intervention.

TL;DR: All trauma deaths occurring in San Diego (California) County during 1 year are reviewed to provide population-based data describing the epidemiology of traumatic death.