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Paul Langan
Researcher at Oak Ridge National Laboratory
Publications - 171
Citations - 12825
Paul Langan is an academic researcher from Oak Ridge National Laboratory. The author has contributed to research in topics: Neutron diffraction & Neutron. The author has an hindex of 44, co-authored 170 publications receiving 10983 citations. Previous affiliations of Paul Langan include United States Department of Energy & Keele University.
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Metal ion roles and the movement of hydrogen during reaction catalyzed by D-xylose isomerase: a joint x-ray and neutron diffraction study.
Andrey Kovalevsky,Leif Hanson,S. Zoë Fisher,Marat Mustyakimov,Sax A. Mason,V. Trevor Forsyth,Matthew P. Blakeley,David A. Keen,Trixie Wagner,H. L. Carrell,Amy K. Katz,Jenny P. Glusker,Paul Langan,Paul Langan +13 more
TL;DR: The structure of the metalloenzyme D-xylose isomerase is determined by neutron diffraction in order to locate H atoms (or their isotope D) and the results lead to new suggestions as to how changes might take place over the course of the reaction.
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Effect of lignin content on changes occurring in poplar cellulose ultrastructure during dilute acid pretreatment
Qining Sun,Marcus Foston,Xianzhi Meng,Daisuke Sawada,Sai Venkatesh Pingali,Hugh O'Neill,Hongjia Li,Charles E. Wyman,Paul Langan,Arthur J. Ragauskas,Rajeev Kumar +10 more
TL;DR: Overall, the results indicate a strong influence of lignin content on cellulose ultrastructural changes occurring during DAP, which might ultimately have large implications with respect to enzymatic deconstruction efforts.
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Neutron crystallography: opportunities, challenges, and limitations
TL;DR: In this review of recently determined neutron structures, a theme emerges of a field currently expanding beyond its traditional boundaries, to address larger and more complex problems, with smaller samples and shorter data collection times, and employing more sophisticated structure determination and refinement methods.
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Generalized X-ray and neutron crystallographic analysis: more accurate and complete structures for biological macromolecules
TL;DR: X-ray and neutron crystallographic data have been combined in a joint structure-refinement procedure that has been developed using recent advances in modern computational methodologies, including cross-validated maximum-likelihood target functions with gradient-based optimization and simulated annealing.
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Ionic-liquid induced changes in cellulose structure associated with enhanced biomass hydrolysis.
TL;DR: In this study, the factor most clearly associated with enhanced biomass hydrolysis is the conversion of cellulose fibers from the cellulose I to the cellulOSE II crystal phase.