P
Paul Matsudaira
Researcher at National University of Singapore
Publications - 230
Citations - 21743
Paul Matsudaira is an academic researcher from National University of Singapore. The author has contributed to research in topics: Actin & Villin. The author has an hindex of 68, co-authored 229 publications receiving 21008 citations. Previous affiliations of Paul Matsudaira include Singapore–MIT alliance & Brigham and Women's Hospital.
Papers
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Journal ArticleDOI
Recombinant expression of the brush border myosin i heavy chain
TL;DR: Any cellular factor required for the general membrane localization or biochemical activity of brush border myosin I is present in COS cells as well as intestinal epithelium.
Journal ArticleDOI
Depth resolved hyperspectral imaging spectrometer based on structured light illumination and Fourier transform interferometry.
TL;DR: The proposed scheme is validated with in vitro specimens including fluorescent solution and fluorescent beads with known spectra and is further demonstrated in quantifying spectra from 3D resolved features in biological specimens.
Correlation of cell membrane dynamics and cell motility
Merlin Veronika,Roy E. Welsch,Roy E. Welsch,Alvin Ng,Paul Matsudaira,Jagath C. Rajapakse,Jagath C. Rajapakse +6 more
TL;DR: In this article, the authors proposed algorithms to extract edge features along the entire cell periphery such as protrusion and retraction velocity, which constitute a unique set of multivariate time-lapse edge features that are then used to profile subclasses of cell dynamics by unsupervised clustering.
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Antibodies to T- and L-isoforms of the cytoskeletal protein, fimbrin, in patients with systemic lupus erythematosus.
E C De Mendonca Neto,Ashok A. Kumar,Nancy A. Shadick,A M Michon,Paul Matsudaira,Roger B. Eaton,Priti Kumar,Peter H. Schur +7 more
TL;DR: Sera from normals and from patients with systemic lupus erythematosus, juvenile arthritis, rheumatoid arthritis, Sjögren's syndrome, osteoarthritis, vasculitis, scleroderma, and mixed connective tissue disease were tested for the presence of antibodies to T- and L-fim Brin by ELISA, using purified recombinant fimbrin.
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STORM: a general model to determine the number and adaptive changes of epithelial stem cells in teleost, murine and human intestinal tracts.
TL;DR: A two-dimensional model, named STORM, is developed that is able to provide quick results for stem cell number and its adaptive changes, which is not easy to measure through experiments, and its general applicability to different species makes it a valuable tool for analysis of intestinal stem cells under various pathological conditions.