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Paul N. Levett
Researcher at Saskatchewan Disease Control Laboratory
Publications - 142
Citations - 9277
Paul N. Levett is an academic researcher from Saskatchewan Disease Control Laboratory. The author has contributed to research in topics: Leptospirosis & Leptospira. The author has an hindex of 44, co-authored 137 publications receiving 8486 citations. Previous affiliations of Paul N. Levett include University of the West Indies & Centers for Disease Control and Prevention.
Papers
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Journal ArticleDOI
Leptospirosis: a zoonotic disease of global importance
Ajay R. Bharti,Jarlath E. Nally,Jessica N. Ricaldi,Michael A. Matthias,Monica M. Diaz,Michael A. Lovett,Paul N. Levett,Robert H. Gilman,Michael R. Willig,Eduardo Gotuzzo,Joseph M. Vinetz +10 more
TL;DR: The completion of the genome sequence of Leptospira interrogans serovar lai, and other continuing leptospiral genome sequencing projects, promise to guide future work on the disease.
Book ChapterDOI
Leptospirosis in Humans
David A. Haake,Paul N. Levett +1 more
TL;DR: Data emerging from prospective surveillance studies suggest that most human leptospiral infections in endemic areas are mild or asymptomatic, and patients progressing to multisystem organ failure have widespread hematogenous dissemination of pathogens.
Journal ArticleDOI
The Leptospiral Major Outer Membrane Protein LipL32 Is a Lipoprotein Expressed during Mammalian Infection
David A. Haake,David A. Haake,Garlo Chao,Richard L. Zuerner,Jeanne K. Barnett,Dean Barnett,Mary K. Mazel,James Matsunaga,James Matsunaga,Paul N. Levett,Carole A. Bolin +10 more
TL;DR: The cloning of the gene encoding the 32-kDa lipoprotein, designated LipL32, the most prominent protein in the leptospiral protein profile, is reported, indicating that LipL 32 may be important in the pathogenesis, diagnosis, and prevention ofLeptospirosis.
Journal ArticleDOI
Atopic dermatitis is associated with a functional mutation in the promoter of the C-C chemokine RANTES
Renate Nickel,Renate Nickel,Vincenzo Casolaro,Ulrich Wahn,Kirsten Beyer,Kirsten Beyer,Kathleen C. Barnes,Beverly Plunkett,Linda R. Freidhoff,Claudia Sengler,James R. Plitt,Robert P. Schleimer,Luis Caraballo,Raana P. Naidu,Paul N. Levett,Terri H. Beaty,Shau Ku Huang +16 more
TL;DR: The findings suggest that the mutant allele of the RANTES gene contributes to the development of atopic dermatitis and its potential role in other inflammatory and infectious disorders, particularly among individuals of African ancestry, remains to be determined.
Journal ArticleDOI
Detection of pathogenic leptospires by real-time quantitative PCR.
Paul N. Levett,Roger E. Morey,Renee L. Galloway,Danielle E Turner,Arnold G. Steigerwalt,Leonard W. Mayer +5 more
TL;DR: A real-time PCR assay was developed using a 423 bp target on the lipL32 gene, which is conserved among pathogenic serovars of LEPTOSPIRA, which has the potential to facilitate rapid, sensitive diagnosis of acute leptospirosis.