P
Paul Roschger
Researcher at McGill University
Publications - 259
Citations - 13886
Paul Roschger is an academic researcher from McGill University. The author has contributed to research in topics: Bone remodeling & Bone mineral. The author has an hindex of 62, co-authored 253 publications receiving 12651 citations.
Papers
More filters
Journal ArticleDOI
Structure and mechanical quality of the collagen–mineral nano-composite in bone
TL;DR: In this paper, the properties of the organic matrix as well as the geometrical arrangement of the two components might have a much larger influence on the properties than traditionally assumed, and some recent results from experiment and numerical modeling leading to these ideas are reviewed.
Journal ArticleDOI
Bone mineralization density distribution in health and disease
TL;DR: BMDD measurements combined with other scanning techniques like nanoindentation, Fourier transform infrared spectroscopy and small angle X-ray scattering can provide important insights into the structure-function relation of the bone matrix, and ultimately a better prediction of fracture risk in diseases, and after treatment.
Journal ArticleDOI
Validation of quantitative backscattered electron imaging for the measurement of mineral density distribution in human bone biopsies
TL;DR: For routine clinical research, the method of calibration and standardization of the backscattered electron (BE) signal is validated and detection of the degree of mineralization independently from the actual bone volume seems to be of special interest in the assessment of the effect of treatments for osteoporosis.
Journal ArticleDOI
From brittle to ductile fracture of bone
TL;DR: It is found that the fracture energy changes by two orders of magnitude depending on the collagen orientation, and the angle between collagen and crack propagation direction is decisive in switching between different toughening mechanisms.
Journal ArticleDOI
Alendronate increases degree and uniformity of mineralization in cancellous bone and decreases the porosity in cortical bone of osteoporotic women
TL;DR: Aln treatment increases the degree and uniformity of bone matrix mineralization without affecting the size and habitus of the mineral crystals, and decreases the porosity of the corticalis, which may contribute to the observed reduction in fractures.